Air travel can be safe and well tolerated in patients with clinically stable pulmonary hypertension

…, R Voswinckel, H Tiede, F Lendeckel… - Pulmonary …, 2011 - journals.sagepub.com
Our aim was to determine what proportion of patients with pulmonary hypertension (PH) has
undertaken air travel contrary to the general medical advice and to characterize these …

The sPAP/VO2 ratio during cardiopulmonary exercise testing as predictor of manifest pulmonary hypertension

…, R Voswinckel, M Thamm, F Lendeckel… - 2012 - Eur Respiratory Soc
Background: Pulmonary hypertension (PH) is characterised by an inappropriate increase of
pulmonary artery pressure (PAP) compared to cardiac output. We evaluated the systolic PAP …

Recommendations for the clinical management of patients receiving macitentan for pulmonary arterial hypertension (PAH): a Delphi consensus document

FF Rahaghi, HM Alnuaimat, RLA Awdish… - Pulmonary …, 2017 - journals.sagepub.com
In patients treated with macitentan (Opsumit®, Actelion Pharmaceuticals Ltd., Basel, Switzerland)
for pulmonary arterial hypertension (PAH), prevention and/or effective management of …

[HTML][HTML] Sequence-specific RNA cleavage by PNA conjugates of the metal-free artificial ribonuclease tris (2-aminobenzimidazole)

F Danneberg, A Ghidini… - Beilstein journal of …, 2015 - beilstein-journals.org
Tris (2-aminobenzimidazole) conjugates with antisense oligonucleotides are effective site-specific
RNA cleavers. Their mechanism of action is independent of metal ions. Here we …

[HTML][HTML] Prognostic relevance of miRNA-155 methylation in anaplastic glioma

MG Schliesser, R Claus, T Hielscher, C Grimm… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The outcome of patients with anaplastic gliomas varies considerably depending on single
molecular markers, such as mutations of the isocitrate dehydrogenase (IDH) genes, as well as …

[PDF][PDF] Oral stem/progenitor cells as a possible cell source for dopaminergic neurons and the role of A disintegrin and metalloprotease 17 in neuronal development …

T Schlothauer - 2022 - macau.uni-kiel.de
Stem cells are unspecialized cells with outstanding characteristics: the ability to differentiate
into various cells and potential for continuous self-renewal. They exist in embryos and adult …

Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly (Spermine Acrylamides) for the Treatment of Lung Fibrosis

F Adams, CM Zimmermann, D Baldassi, TM Pehl… - Small, 2023 - Wiley Online Library
RNA interference (RNAi) is an efficient strategy to post‐transcriptionally silence gene
expression. While all siRNA drugs on the market target the liver, the lung offers a variety of …

[HTML][HTML] Serum microRNA-122 predicts survival in patients with liver cirrhosis

O Waidmann, V Köberle, F Brunner, S Zeuzem… - 2012 - journals.plos.org
Background Liver cirrhosis is associated with high morbidity and mortality. MicroRNAs (miRs)
circulating in the blood are an emerging new class of biomarkers. In particular, the serum …

[PDF][PDF] Toward cell-based bone regeneration using autologously available cells

J Husch - 2022 - repository.ubn.ru.nl
Large bone defects and fractures are still clinical problems that require surgical intervention,
especially in a condition where the regenerative process is compromised1. Although …

Cellular mechanisms of depressed atrial contractility in patients with chronic atrial fibrillation

U Schotten, J Ausma, C Stellbrink, I Sabatschus… - Circulation, 2001 - Am Heart Assoc
Background—After cardioversion of atrial fibrillation (AF), the contractile function of the atria
is temporarily impaired. Although this has significant clinical implications, the underlying …