Background Chronic obstructive pulmonary disease (COPD) is a major public health
problem associated with long-term exposure to toxic gases and particles. We examined the …

Field walking tests are commonly employed to evaluate exercise capacity, assess prognosis
and evaluate treatment response in chronic respiratory diseases. In recent years, there has …

Background Acute exacerbations adversely affect patients with chronic obstructive pulmonary
disease (COPD). Macrolide antibiotics benefit patients with a variety of inflammatory …

Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV 1 inadequately describes this …

Background Endobronchial valves that allow air to escape from a pulmonary lobe but not
enter it can induce a reduction in lobar volume that may thereby improve lung function and …

This systematic review examined the measurement properties of the 6-min walk test (6MWT),
incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT) in adults with …

This study examines the hypothesis that the cigarette smoke-induced inflammatory process
is amplified in severe emphysema and explores the association of this response with latent …

Importance Acutely ill inpatients with COVID-19 typically receive antithrombotic therapy,
although the risks and benefits of this intervention among outpatients with COVID-19 have not …

Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity,
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…

Background Cigarette smoking is associated with emphysema and radiographic interstitial
lung abnormalities. The degree to which interstitial lung abnormalities are associated with …