User profiles for Françoise Van Bambeke
Françoise Van BambekeUniversité catholique de Louvain Verified email at uclouvain.be Cited by 13281 |
Antibiotic efflux pumps
F Van Bambeke, E Balzi, PM Tulkens - Biochemical pharmacology, 2000 - Elsevier
Active efflux from procaryotic as well as eucaryotic cells strongly modulates the activity of a
large number of antibiotics. Effective antibiotic transport has now been observed for many …
large number of antibiotics. Effective antibiotic transport has now been observed for many …
[HTML][HTML] Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium
…, A Malfroot, PM Tulkens, F Van Bambeke - Clinical microbiology …, 2007 - Elsevier
Pseudomonas aeruginosa is a major cause of nosocomial infections. This organism shows
a remarkable capacity to resist antibiotics, either intrinsically (because of constitutive …
a remarkable capacity to resist antibiotics, either intrinsically (because of constitutive …
[HTML][HTML] Intracellular Staphylococcus aureus persisters upon antibiotic exposure
…, JY Coppée, C Wolz, T Tenson, F Van Bambeke - Nature …, 2020 - nature.com
Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …
[HTML][HTML] Quinolones in 2005: an update
F Van Bambeke, JM Michot, J Van Eldere… - Clinical Microbiology …, 2005 - Elsevier
Quinolones are one of the largest classes of antimicrobial agents used worldwide. This
review considers the quinolones that are available currently and used widely in Europe (…
review considers the quinolones that are available currently and used widely in Europe (…
[PDF][PDF] Cellular pharmacodynamics and pharmacokinetics of antibiotics: current views and perspectives
F Van Bambeke, M Barcia-Macay, S Lemaire… - Current Opinion in Drug …, 2006 - Citeseer
The treatment of intracellular infections requires the use of antibiotics presenting appropriate
cellular pharmacokinetic and pharmacodynamic properties. These properties, however, …
cellular pharmacokinetic and pharmacodynamic properties. These properties, however, …
Intracellular pharmacodynamics of antibiotics
…, MP Mingeot-Leclercq, F Van Bambeke… - Infectious Disease …, 2003 - id.theclinics.com
Treatment of intracellular bacterial infection remains both a medical and economic challenge.
Pathogens thriving or maintaining themselves in cells, or simply taking transient refuge …
Pathogens thriving or maintaining themselves in cells, or simply taking transient refuge …
Renaissance of antibiotics against difficult infections: focus on oritavancin and new ketolides and quinolones
F Van Bambeke - Annals of medicine, 2014 - Taylor & Francis
Lipoglycopeptide, ketolide, and quinolone antibiotics are currently in clinical development,
with specific advantages over available molecules within their respective classes. The …
with specific advantages over available molecules within their respective classes. The …
Pharmacodynamic Evaluation of the Intracellular Activities of Antibiotics against Staphylococcus aureus in a Model of THP-1 Macrophages
…, PM Tulkens, F Van Bambeke - Antimicrobial agents …, 2006 - Am Soc Microbiol
The pharmacodynamic properties governing the activities of antibiotics against intracellular
Staphylococcus aureus are still largely undetermined. Sixteen antibiotics of seven different …
Staphylococcus aureus are still largely undetermined. Sixteen antibiotics of seven different …
[HTML][HTML] Glycopeptide antibiotics: from conventional molecules to new derivatives
F Van Bambeke, Y Van Laethem, P Courvalin… - Drugs, 2004 - Springer
Vancomycin and teicoplanin are still the only glycopeptide antibiotics available for use in
humans. Emergence of resistance in enterococci and staphylococci has led to restriction of …
humans. Emergence of resistance in enterococci and staphylococci has led to restriction of …
Antibiotic efflux pumps in prokaryotic cells: occurrence, impact on resistance and strategies for the future of antimicrobial therapy
F Van Bambeke, Y Glupczynski, P Plesiat… - Journal of …, 2003 - academic.oup.com
Originally described in bacteria, drug transporters (or efflux pumps) are now recognized as
major determinants in the modulation of the accumulation and efflux of antibacterials in …
major determinants in the modulation of the accumulation and efflux of antibacterials in …