Early availability of information on bacterial pathogens and their antimicrobial susceptibility
is of key importance for the management of infectious diseases patients. Currently, using …

Antibiotic therapy of infections caused by the emerging pathogen Mycobacterium abscessus
is challenging due to the organism's natural resistance toward most clinically available …

Objectives To develop a robust phenotypic antimicrobial susceptibility testing (AST) method
with a correctly set breakpoint for pretomanid (Pa), the most recently approved anti-…

Rationale Bedaquiline has been classified as a group A drug for the treatment of multidrug-resistant
tuberculosis (MDR-TB) by the World Health Organization; however, globally …

Background Avibactam is a novel broad-range β-lactamase inhibitor active against Ambler
class A (including ESBL and KPC) and some Ambler class C and D (eg OXA-48) enzymes. …

Objectives Antibiotic therapy of pulmonary Mycobacterium abscessus infection is based on
a combination treatment including clarithromycin. Recent data demonstrated that M. …

Objectives The ribosomal methylase Erm(41) confers inducible resistance to macrolides in
Mycobacterium abscessus. The aim of this work was to systematically study and compare …

Background Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not
detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB …

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium
tuberculosis complex (Mtbc) isolates challenges tuberculosis (TB) control worldwide […

Reliable identification of carbapenemase-producing members of the family Enterobacteriaceae
is necessary to limit their spread. This study aimed to develop a diagnostic flow chart …