[HTML][HTML] Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers

…, A Corrales, I Ferraz-Amaro, F Genre… - Autoimmunity …, 2016 - Elsevier
Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process. …

[HTML][HTML] Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review

R López-Mejías, S Castañeda, F Genre… - Autoimmunity …, 2018 - Elsevier
Immunoglobulin-A vasculitis (IgAV) is classically a childhood small-sized blood vessel vasculitis
with predominant involvement of the skin. Gastrointestinal and joint manifestations are …

[HTML][HTML] Adipokines, biomarkers of endothelial activation, and metabolic syndrome in patients with ankylosing spondylitis

F Genre, R López-Mejías, JA Miranda-Filloy… - BioMed research …, 2014 - hindawi.com
Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease associated with
accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. AS patients also …

Integrative analysis reveals a molecular stratification of systemic autoimmune diseases

…, A Corrales Martínez, F Genre… - Arthritis & …, 2021 - Wiley Online Library
Objective Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes
early diagnosis and effective treatment, issues that may be addressed if patients could be …

[PDF][PDF] Rapid beneficial effect of the IL-6 receptor blockade on insulin resistance and insulin sensitivity in non-diabetic patients with rheumatoid arthritis

…, R López-Mejías, F Genre… - Clin Exp …, 2019 - wiredspace.wits.ac.za
Objective In patients with rheumatoid arthritis (RA), insulin resistance (IR), a component of
the metabolic syndrome, is closely linked to the systemic inflammation induced by …

[HTML][HTML] Endothelin-1 as a biomarker of idiopathic pulmonary fibrosis and interstitial lung disease associated with autoimmune diseases

V Pulito-Cueto, F Genre, R López-Mejías… - International journal of …, 2023 - mdpi.com
The aim of this study was to determine the role of endothelin-1 (ET-1), a molecule involved
in multiple vascular and fibrosing abnormalities, as a biomarker of interstitial lung disease (…

[HTML][HTML] A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis

R López-Mejías, FD Carmona, S Castañeda, F Genre… - Scientific reports, 2017 - nature.com
The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To
increase the current knowledge on the genetic component of this vasculitis we performed the …

[HTML][HTML] Irisin as a novel biomarker of subclinical atherosclerosis, cardiovascular risk and severe disease in axial spondyloarthritis

…, I Ferraz-Amaro, MÁ González-Gay, F Genre - Frontiers in …, 2022 - frontiersin.org
Introduction Patients with axial spondyloarthritis (axSpA) have a high disease burden mainly
due to the rheumatic disease itself, and also exhibit accelerated atherosclerosis, that leads …

Sex differences in cardiovascular and disease-related features in axial spondyloarthritis. A multicenter study of 912 patients

I Ferraz-Amaro, F Genre, R Blanco, A Corrales… - Seminars in Arthritis and …, 2023 - Elsevier
Objectives To determine the potential impact of sex-specific disease-related characteristics
on cardiovascular (CV) disease in axial spondyloarthritis (axSpA). Methods Cross-sectional …

[HTML][HTML] Association of HLA-B* 41: 02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status

R López-Mejías, F Genre, BS Pérez… - Arthritis research & …, 2015 - Springer
Introduction A study was conducted to determine whether the human leukocyte antigen (HLA)
B alleles are implicated in the susceptibility to Henoch-Schönlein purpura (HSP) in the …