Background Standard chemotherapy does not lead to long-term survival in patients with
malignant pleural mesothelioma. Malignant pleural mesothelioma is strongly dependent on …

Quality of life measures are increasingly used as important efficacy endpoints in studies of
drugs for asthma. The purpose of this study was to assess both the sensitivity to change and …

OBJECTIVES:: The purpose of this study was to describe the experience with the anti-angiogenic
agent thalidomide in the treatment of patients with a malignant pleural mesothelioma (…

Background Although proxies of patients with chronic obstructive pulmonary disease (COPD)
need health-related knowledge to support patients in managing their disease, their current …

Tiotropium (Spiriva®) is a new once-daily inhaled anticholinergic that has its effect through
prolonged muscarinic (M) 3 receptor antagonism. It has a clinically documented, long …

Presynaptic cholinergic markers could be used for estimating the integrity of the cholinergic
systems in the human brain with brain imaging techniques such as Single-photon emission …

Fecal microbiota transplantation (FMT) is a procedure used to treat diseases related to
microbiome imbalances. We discuss how ecological principles can inform the design of FMT …

… Custers MD b , Jan H. Vercoulen PhD d , Guus M. Asijee PhD e , Jean W. Muris MD, PhD f
, Lowie EGW Vanfleteren MD, PhD a , Frits ME Franssen MD, PhD a , Emiel FM Wouters MD, …

In this paper, a review of long-term retention of basic science knowledge is presented. First,
it is argued that retention of this knowledge has been a long-standing problem in medical …

7006 Background: Standard chemotherapy treatment does not lead to long-term survival;
new treatment approaches are required. MPM is known for its high vessel count and levels of …