Background In critically ill patients, antibiotic therapy is of great importance but long duration
of treatment is associated with the development of antimicrobial resistance. Procalcitonin is …

Background Whether addition of corticosteroids to antibiotic treatment benefits patients with
community-acquired pneumonia who are not in intensive care units is unclear. We aimed to …

Scope The Dutch Working Party on Antibiotic Policy constituted a multidisciplinary expert
committee to provide evidence-based recommendation for the use of antibacterial therapy in …

Objective To evaluate whether the potential of statins to lower the risk of infections as
published in observational studies is causal. Design Systematic review and meta-analysis of …

Objective: To assess the association of systemic inflammation and outcome after major
abdominal surgery. Background: Major abdominal surgery carries a high postoperative morbidity …

Objective: Remifentanil is an ultra-short-acting opioid that is used commonly during both
short-term and prolonged surgery. This review investigated associations of intraoperative …

Background Chronic thoracic pain after cardiac surgery is a serious condition affecting
many patients. The aim of this study was to identify predictors for chronic thoracic pain after …

Background: Recent prognostic studies have shown that previous treatment with statins is
associated with a better outcome in patients admitted to hospital with pneumonia. Because of …

Appropriate antibiotic treatment for respiratory tract infections (RTIs) necessitates rapid and
accurate diagnosis of microbial etiology, which remains challenging despite recent …

This study aims to assess how clinical outcomes of immunotherapy in real-world (effectiveness)
correspond to outcomes in clinical trials (efficacy) and to look into factors that might …