The scientific study of vertebrate-host acquired immunity to infectious disease began in
1882 with the development by Pasteur of vaccines to fowl cholera and to rabies. The dual …

Precisely three decades have elapsed since Schade and Caroline described evidence for
the presence of strong iron binding proteins in egg white and plasma, and suggested that the …

Possible Mechanisms Inasmuch as the growth requirement of ap-proximately 0.4 to 4.0, M
iron is similar for cells of animals, plants, and microorganisms (202), it would appear at first …

BACKGROUND: To successfully sustain an infection, nearly all bacteria, fungi and protozoa
require a continuous supply of host iron. METHODS: Literature review. RESULTS: …

WITHIN the past half century, the doctrine of the biochemical unity of living matter has become
well established. Metabolic pathways as well as methods of storage, transfer, and use of …

Pregnancy has been known for some time to be associated with depressed aspects of cell-mediated
immunity (CMI) that permit fetal retention but that also may interfere with resistance …

Iron is an oxidant as well as a nutrient for invading microbial and neoplastic cells. Excessive
iron in specific tissues and cells (iron loading) promotes development of infection, neoplasia…

Cells of nearly all forms of life require iron. The metal provides electron transport proteins with
a wide range of redox potentials. It is an integral component of oxygen carrier proteins and …

Lactoferrin (Lf), a natural defence iron‐binding protein, has been found to possess
antibacterial, antimycotic, antiviral, antineoplastic and anti‐inflammatory activity. The protein is …

The prevalence of asthma and allergic disease in children has been increasing in developed
countries, but there is little information on these trends in Africa. The aim of this study was …