Allergic rhinitis (AR) and asthma represent global health problems for all age groups.
Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on …

The classic phenotype of IgE-mediated asthma starting in childhood is now clearly defined.
However, many other phenotypes of asthma in childhood as well in adulthood are being …

Patients with severe refractory asthma pose a major healthcare problem. Over the last decade
it has become increasingly clear that, for the development of new targeted therapies, there …

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society, …

Background Many patients with severe asthma require regular treatment with oral glucocorticoids
despite the use of high-dose inhaled therapy. However, the regular use of systemic …

According to international guidelines, the level and adjustment of antiinflammatory treatment
for asthma are based solely on symptoms and lung function. We investigated whether a …

Background Severe asthma is characterized by difficulty to achieve disease control despite
high-intensity treatment. However, prevalence figures of severe asthma are lacking, whereas …

U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical
companies and six patient organisations with the objective of improving the understanding …

BACKGROUND: Exhaled breath contains thousands of volatile organic compounds (VOCs)
that could serve as biomarkers of lung disease. Electronic noses can distinguish VOC …

Background Monitoring sputum eosinophils in asthma predicts exacerbations and improves
management of asthma. Thus far, blood eosinophils and FE NO show contradictory results …