Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: the TIME2 randomized …
HE Davies, EK Mishra, BC Kahan, JM Wrightson… - Jama, 2012 - jamanetwork.com
Context Malignant pleural effusion causes disabling dyspnea in patients with a short life
expectancy. Palliation is achieved by fluid drainage, but the most effective first-line method has …
expectancy. Palliation is achieved by fluid drainage, but the most effective first-line method has …
Clinical outcomes of indwelling pleural catheter-related pleural infections: an international multicenter study
Background Indwelling pleural catheters (IPCs) offer effective control of malignant pleural
effusions (MPEs). IPC-related infection is uncommon but remains a major concern. Individual …
effusions (MPEs). IPC-related infection is uncommon but remains a major concern. Individual …
British thoracic society guideline for pleural disease
Conservative management can be considered for the treatment of minimally symptomatic (ie,
no significant pain or breathlessness and no physiological compromise) or asymptomatic …
no significant pain or breathlessness and no physiological compromise) or asymptomatic …
Clinically important factors influencing the diagnostic measurement of pleural fluid pH and glucose
NM Rahman, EK Mishra, HE Davies… - American journal of …, 2008 - atsjournals.org
Rationale: Accurate pleural fluid pH and glucose measurement is a key component in the
diagnosis and management of patients with pleural effusion. Standardized methods of pleural …
diagnosis and management of patients with pleural effusion. Standardized methods of pleural …
Comparing cost of indwelling pleural catheter vs talc pleurodesis for malignant pleural effusion
BACKGROUND Malignant pleural effusion is associated with short life expectancy and
significant morbidity. A randomized controlled trial comparing indwelling pleural catheters (IPCs) …
significant morbidity. A randomized controlled trial comparing indwelling pleural catheters (IPCs) …
Diagnostic accuracy, safety and utilisation of respiratory physician-delivered thoracic ultrasound
…, HE Davies, JM Wrightson, EK Mishra… - Thorax, 2010 - thorax.bmj.com
Background Thoracic ultrasound-guided pleural procedures are associated with fewer
adverse events than ‘blind’ procedures for patients with pleural effusion. Ultrasound is …
adverse events than ‘blind’ procedures for patients with pleural effusion. Ultrasound is …
Randomized controlled trial of urokinase versus placebo for nondraining malignant pleural effusion
EK Mishra, AO Clive, GH Wills, HE Davies… - American journal of …, 2018 - atsjournals.org
Rationale: Patients with malignant pleural effusion experience breathlessness, which is
treated by drainage and pleurodesis. Incomplete drainage results in residual dyspnea and …
treated by drainage and pleurodesis. Incomplete drainage results in residual dyspnea and …
Cost‐effectiveness of indwelling pleural catheter compared with talc in malignant pleural effusion
Background and objective Malignant pleural effusion is associated with morbidity and mortality.
A randomized controlled trial previously compared clinical outcomes and resource use …
A randomized controlled trial previously compared clinical outcomes and resource use …
[HTML][HTML] Defining the minimal important difference for the visual analogue scale assessing dyspnea in patients with malignant pleural effusions
EK Mishra, JP Corcoran, RJ Hallifax, J Stradling… - PloS one, 2015 - journals.plos.org
Background The minimal important difference (MID) is essential for interpreting the results
of randomised controlled trials (RCTs). Despite a number of RCTs in patients with malignant …
of randomised controlled trials (RCTs). Despite a number of RCTs in patients with malignant …
Chemotherapy should not be withheld from patients with an indwelling pleural catheter for malignant pleural effusion
A Morel, E Mishra, L Medley, NM Rahman, J Wrightson… - Thorax, 2011 - thorax.bmj.com
A 1e12% rate of pleural infection has been observed in patients with an indwelling pleural
catheter (IPC) to manage malignant pleural effusion (MPE), leading to concern that systemic …
catheter (IPC) to manage malignant pleural effusion (MPE), leading to concern that systemic …