A molecular basis for bidirectional communication between the immune and neuroendocrine systems.
JE Blalock - Physiological reviews, 1989 - journals.physiology.org
2 J. EDWIN BLALOCK Vdume 69 systems, which we term neuroimmunoendocrinology(73).
Although this field was, in part, defined in 1977 (13), its origins are much earlier and may …
Although this field was, in part, defined in 1977 (13), its origins are much earlier and may …
The syntax of immune-neuroendocrine communication
JE Blalock - Immunology today, 1994 - cell.com
… Here, Edwin Blalock discusses bow these shared ligands and receptors are used as a
common chemical language for communication within and between the immune and …
common chemical language for communication within and between the immune and …
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
…, FS Galin, G Folkerts, FP Nijkamp, JE Blalock - Nature medicine, 2006 - nature.com
We describe the tripeptide neutrophil chemoattractant N-acetyl Pro-Gly-Pro (PGP), derived
from the breakdown of extracellular matrix (ECM), which shares sequence and structural …
from the breakdown of extracellular matrix (ECM), which shares sequence and structural …
Interactions between the neuroendocrine and immune systems: common hormones and receptors.
DA Weigent, JE Blalock - Immunological reviews, 1987 - europepmc.org
The studies reviewed here support a molecular basis for bidirectional communication
between the immune and neuroendocrine systems. The main findings can be summarized as …
between the immune and neuroendocrine systems. The main findings can be summarized as …
Human lymphocyte production of corticotropin and endorphin-like substances: association with leukocyte interferon.
EM Smith, JE Blalock - … of the National Academy of Sciences, 1981 - National Acad Sciences
Human leukocyte interferon (hIFN-alpha) preparations contain immunologically and
biologically recognizable endorphin and corticotropin-like (ACTH-like) activities. The ACTH …
biologically recognizable endorphin and corticotropin-like (ACTH-like) activities. The ACTH …
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
…, SM Rowe, JP Clancy, JE Blalock - The Journal of …, 2008 - journals.aai.org
Chronic neutrophilic inflammation is a manifestation of a variety of lung diseases including
cystic fibrosis (CF). There is increasing evidence that fragments of extracellular matrix proteins…
cystic fibrosis (CF). There is increasing evidence that fragments of extracellular matrix proteins…
[PDF][PDF] Activated PMN exosomes: pathogenic entities causing matrix destruction and disease in the lung
…, MT Dransfield, R Tirouvanziam, A Gaggar, JE Blalock - Cell, 2019 - cell.com
Here, we describe a novel pathogenic entity, the activated PMN (polymorphonuclear leukocyte,
ie, neutrophil)-derived exosome. These CD63 + /CD66b + nanovesicles acquire surface-…
ie, neutrophil)-derived exosome. These CD63 + /CD66b + nanovesicles acquire surface-…
A Critical Role for LTA4H in Limiting Chronic Pulmonary Neutrophilic Inflammation
Leukotriene A 4 hydrolase (LTA 4 H) is a proinflammatory enzyme that generates the
inflammatory mediator leukotriene B 4 (LTB 4 ). LTA 4 H also possesses aminopeptidase activity …
inflammatory mediator leukotriene B 4 (LTB 4 ). LTA 4 H also possesses aminopeptidase activity …
[HTML][HTML] MMP generated matrikines
JM Wells, A Gaggar, JE Blalock - Matrix biology, 2015 - Elsevier
Matrikines originate from the fragmentation of extracellular matrix proteins and regulate cellular
activities by interacting with specific receptors. Matrikines are implicated in inflammation, …
activities by interacting with specific receptors. Matrikines are implicated in inflammation, …
Human leukocyte interferon: structural and biological relatedness to adrenocorticotropic hormone and endorphins.
JE Blalock, EM Smith - … of the National Academy of Sciences, 1980 - National Acad Sciences
Anti-alpha-corticotropin [anti-ACTH alpha (1-13)](also alpha-melanotropin) and anti-gamma-endorphin
antisera neutralized human leukocyte interferon activity but not fibroblast …
antisera neutralized human leukocyte interferon activity but not fibroblast …