Smoking is one of the major lifestyle factors influencing the health of human beings. Life-long
cigarette smokers have a higher prevalence of common diseases such as atherosclerosis …

The pathogenesis and clinical manifestations of COPD are not restricted to pulmonary
inflammation and structural remodeling. Rather, this disorder is associated with clinically …

… EC Creutzberg2, … Dentener MA, Creutzberg EC, Schols AM, et al. Systemic anti-inflammatory
mediators in COPD: increase in soluble interleukin 1 receptor II during treatment of …

OBJECTIVE: The present study focuses on the prevalence of nutritional depletion in relation
to functional performance, airflow limitation, experienced dyspnoea and health status in a …

Background: Guidelines recommend inhaled corticosteroids (ICS) as maintenance
treatment for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator …

OBJECTIVE: Weight loss and muscle wasting adversely affect morbidity and mortality in
patients with chronic obstructive pulmonary disease (COPD). Maintenance systemic …

Background: Muscle wasting and decreased muscle oxidative capacity commonly occur in
patients with chronic obstructive pulmonary disease (COPD). Polyunsaturated fatty acids (…

Aims: To describe the distribution of COPD disease severity in primary care based on airway
obstruction, and to assess the extent to which dyspnoea scores, body mass index (BMI) and …

Chronic obstructive pulmonary disease (COPD) is a syndrome of chronic wasting, in part
associated with a chronic inflammatory response. The aim of this study was to investigate cross-…

Study objectives Skeletal muscle weakness commonly occurs in patients with COPD. Long-term
use of systemic glucocorticosteroids further contributes to muscle weakness. Anabolic …