User profiles for Dermot O'Callaghan
Dermot O'CallaghanVerified email at mater.ie Cited by 4449 |
Pulmonary arterial hypertension in patients treated by dasatinib
…, D Natali, C Guignabert, F Perros, DS O'Callaghan… - Circulation, 2012 - Am Heart Assoc
Background— The French pulmonary hypertension (PH) registry allows the survey of
epidemiological trends. Isolated cases of precapillary PH have been reported in patients who have …
epidemiological trends. Isolated cases of precapillary PH have been reported in patients who have …
[HTML][HTML] A hemodynamic study of pulmonary hypertension in sickle cell disease
…, A Yaïci, L Hajji, DS O'Callaghan… - … England Journal of …, 2011 - Mass Medical Soc
Background The prevalence and characteristics of pulmonary hypertension in adults with
sickle cell disease have not been clearly established. Methods In this prospective study, we …
sickle cell disease have not been clearly established. Methods In this prospective study, we …
[HTML][HTML] The role of inflammation in the pathogenesis of non-small cell lung cancer
DS O'Callaghan, D O'Donnell, F O'Connell… - Journal of thoracic …, 2010 - Elsevier
The link between chronic immune activation and tumorigenesis is well established. Compelling
evidence has accumulated that histologic assessment of infiltration patterns of different …
evidence has accumulated that histologic assessment of infiltration patterns of different …
Clinical Outcomes of Pulmonary Arterial Hypertension in Patients Carrying an ACVRL1 (ALK1) Mutation
…, A Fraisse, O Sitbon, DS O'Callaghan… - American journal of …, 2010 - atsjournals.org
Rationale: Activin A receptor type II-like kinase-1 (ACVRL1, also known as ALK1) mutation is
a cause of hereditary hemorrhagic telangiectasia (HHT) and/or heritable pulmonary arterial …
a cause of hereditary hemorrhagic telangiectasia (HHT) and/or heritable pulmonary arterial …
A proof-of-concept, randomized, controlled trial of omalizumab in patients with severe, difficult-to-control, nonatopic asthma
…, F de Blay, LJ Couderc, A Didier, DS O'Callaghan… - Chest, 2013 - Elsevier
Background While up to 50% of patients with severe asthma have no evidence of allergy,
IgE has been linked to asthma, irrespective of atopic status. Omalizumab, an anti-IgE …
IgE has been linked to asthma, irrespective of atopic status. Omalizumab, an anti-IgE …
Treatment of pulmonary arterial hypertension with targeted therapies
Pulmonary arterial hypertension (PAH) is a rare disorder characterized by progressive
obliteration of the pulmonary microvasculature that results in elevated pulmonary vascular …
obliteration of the pulmonary microvasculature that results in elevated pulmonary vascular …
Usefulness of first-line combination therapy with epoprostenol and bosentan in pulmonary arterial hypertension: an observational study
K Kemp, L Savale, DS O'Callaghan, X Jaïs… - The Journal of heart and …, 2012 - Elsevier
BACKGROUND: Recent guidelines have proposed first-line combination therapy as a
potential strategy for the treatment of functional class IV pulmonary arterial hypertension (PAH). …
potential strategy for the treatment of functional class IV pulmonary arterial hypertension (PAH). …
Efficacy, safety and pharmacokinetics of bosentan in portopulmonary hypertension
Data on treatment of patients with portopulmonary hypertension (PoPH) are limited, as they
are usually excluded from randomised controlled trials with pulmonary arterial hypertension (…
are usually excluded from randomised controlled trials with pulmonary arterial hypertension (…
[HTML][HTML] Pulmonary veno-occlusive disease: recent progress and current challenges
Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary arterial
hypertension characterised by a progressive obstruction of small pulmonary veins that leads to …
hypertension characterised by a progressive obstruction of small pulmonary veins that leads to …
Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer
The impact of host immunity on outcome in nonsmall cell lung cancer (NSCLC) is controversial.
We examined the relationship between lymphoid infiltration patterns in NSCLC and …
We examined the relationship between lymphoid infiltration patterns in NSCLC and …