Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy
…, G Castelli, E Catena, S Cattaneo, D Chiumello… - Jama, 2020 - jamanetwork.com
Importance In December 2019, a novel coronavirus (severe acute respiratory syndrome
coronavirus 2 [SARS-CoV-2]) emerged in China and has spread globally, creating a pandemic. …
coronavirus 2 [SARS-CoV-2]) emerged in China and has spread globally, creating a pandemic. …
Risk factors associated with mortality among patients with COVID-19 in intensive care units in Lombardy, Italy
…, E Catena, S Celotti, S Cerutti, D Chiumello… - JAMA internal …, 2020 - jamanetwork.com
Importance Many patients with coronavirus disease 2019 (COVID-19) are critically ill and
require care in the intensive care unit (ICU). Objective To evaluate the independent risk factors …
require care in the intensive care unit (ICU). Objective To evaluate the independent risk factors …
[HTML][HTML] COVID-19 pneumonia: different respiratory treatments for different phenotypes?
L Gattinoni, D Chiumello, P Caironi, M Busana… - Intensive care …, 2020 - Springer
The Surviving Sepsis Campaign panel recently recommended that “mechanically ventilated
patients with COVID-19 should be managed similarly to other patients with acute respiratory …
patients with COVID-19 should be managed similarly to other patients with acute respiratory …
COVID-19 does not lead to a “typical” acute respiratory distress syndrome
In summary, we found that hypercapnia was common in patients with COVID-19–associated
ARDS while using low VT ventilation. VR was increased in these patients, which reflected …
ARDS while using low VT ventilation. VR was increased in these patients, which reflected …
[HTML][HTML] Lung recruitment in patients with the acute respiratory distress syndrome
…, P Caironi, M Cressoni, D Chiumello… - … England Journal of …, 2006 - Mass Medical Soc
Background In the acute respiratory distress syndrome (ARDS), positive end-expiratory
pressure (PEEP) may decrease ventilator-induced lung injury by keeping lung regions open that …
pressure (PEEP) may decrease ventilator-induced lung injury by keeping lung regions open that …
[HTML][HTML] COVID-19 pneumonia: ARDS or not?
L Gattinoni, D Chiumello, S Rossi - Critical care, 2020 - Springer
Even though it can meet the ARDS Berlin definition [1, 2], the COVID-19 pneumonia is a specific
disease with peculiar phenotypes. Its main characteristic is the dissociation between the …
disease with peculiar phenotypes. Its main characteristic is the dissociation between the …
Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study
MLNG Malbrain, D Chiumello, P Pelosi… - Critical care …, 2005 - journals.lww.com
Objective: Intraabdominal hypertension is associated with significant morbidity and mortality
in surgical and trauma patients. The aim of this study was to assess, in a mixed population …
in surgical and trauma patients. The aim of this study was to assess, in a mixed population …
Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome
D Chiumello, E Carlesso, P Cadringher… - American journal of …, 2008 - atsjournals.org
Rationale: Lung injury caused by a ventilator results from nonphysiologic lung stress (transpulmonary
pressure) and strain (inflated volume to functional residual capacity ratio). …
pressure) and strain (inflated volume to functional residual capacity ratio). …
Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study
MLNG Malbrain, D Chiumello, P Pelosi, A Wilmer… - Intensive care …, 2004 - Springer
Objective Although intra-abdominal hypertension (IAH) can cause dysfunction of several
organs and raise mortality, little information is available on the incidence and risk factors for IAH …
organs and raise mortality, little information is available on the incidence and risk factors for IAH …
[HTML][HTML] Ventilator-related causes of lung injury: the mechanical power
…, M Gotti, C Chiurazzi, E Carlesso, D Chiumello… - Intensive care …, 2016 - Springer
Purpose We hypothesized that the ventilator-related causes of lung injury may be unified in
a single variable: the mechanical power. We assessed whether the mechanical power …
a single variable: the mechanical power. We assessed whether the mechanical power …