User profiles for David A. Johnston

David Johnston

University of Southampton
Verified email at soton.ac.uk
Cited by 6396

[HTML][HTML] The genome of the blood fluke Schistosoma mansoni

…, H Hirai, Y Hirai, R Houston, A Ivens, DA Johnston… - Nature, 2009 - nature.com
Schistosoma mansoni is responsible for the neglected tropical disease schistosomiasis that
affects 210 million people in 76 countries. Here we present analysis of the 363 megabase …

Effects of supplier trust on performance of cooperative supplier relationships

DA Johnston, DM McCutcheon, FI Stuart… - Journal of operations …, 2004 - Elsevier
This study tests a path analytic model of buyer–supplier relationships, linking the supplier’s
level of trust to three categories of inter-firm cooperative behaviors and these behaviors to …

Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection

…, H Kim, KL Cox, JP Kerr, DA Johnston… - Blood, The Journal …, 2010 - ashpublications.org
Rituximab, a monoclonal antibody that targets CD20 on B cells, is now central to the treatment
of a variety of malignant and autoimmune disorders. Despite this success, a substantial …

[HTML][HTML] Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

NJ Albargothy, DA Johnston, M MacGregor-Sharp… - Acta …, 2018 - Springer
Tracers injected into CSF pass into the brain alongside arteries and out again. This has
been recently termed the “glymphatic system” that proposes tracers enter the brain along …

[HTML][HTML] Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy

A Keable, K Fenna, HM Yuen, DA Johnston… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Deposition of amyloid β (Aβ) in the walls of cerebral arteries as cerebral amyloid angiopathy
(CAA) suggests an age-related failure of perivascular drainage of soluble Aβ from the brain. …

Failure of perivascular drainage of β‐amyloid in cerebral amyloid angiopathy

CA Hawkes, N Jayakody, DA Johnston… - Brain …, 2014 - Wiley Online Library
In Alzheimer's disease, amyloid‐β (Aβ) accumulates as insoluble plaques in the brain and
deposits in blood vessel walls as cerebral amyloid angiopathy ( CAA ). The severity of CAA …

The complete mitochondrial genomes of Schistosoma haematobium and Schistosoma spindale and the evolutionary history of mitochondrial genome changes among …

…, AE Lockyer, BL Webster, DA Johnston… - Molecular phylogenetics …, 2006 - Elsevier
Complete mitochondrial genome sequences for the schistosomes Schistosoma haematobium
and Schistosoma. spindale have been characterized. S. haematobium is the causative …

Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology?

AT Prach, TA MacDonald, DA Hopwood, DA Johnston - The Lancet, 1997 - thelancet.com
For unknown reasons, the incidence of oesophageal adenocarcinoma is rising rapidly in
the UK1 and the USA. 2 In particular, in Scotland, the incidence of oesophageal …

[HTML][HTML] A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection

…, M Loxham, S Reikine, A Azim, K Tariq, DA Johnston… - Nature …, 2021 - nature.com
Angiotensin-converting enzyme 2 (ACE2) is the main entry point in airway epithelial cells for
SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion with the …

Extraordinary host switching in siphonostomatoid copepods and the demise of the Monstrilloida: integrating molecular data, ontogeny and antennulary morphology

…, PD Olson, JN Spinks, DA Johnston - Molecular Phylogenetics …, 2007 - Elsevier
Copepods exhibit an astounding variety of lifestyles, host associations and morphology, to
the extent that their crustacean affinities may be obscured. Relationships among the ten …