User profiles for Danny J. Eckert
Danny EckertAdelaide Institute for Sleep Health, Flinders University and Neuroscience Research … Verified email at flinders.edu.au Cited by 13382 |
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …
patients but have not been well characterized. Objectives: To define carefully the proportion …
Pathophysiology of adult obstructive sleep apnea
DJ Eckert, A Malhotra - Proceedings of the American thoracic …, 2008 - atsjournals.org
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive narrowing
or collapse of the pharyngeal airway during sleep. The disorder is associated with major …
or collapse of the pharyngeal airway during sleep. The disorder is associated with major …
Central sleep apnea: pathophysiology and treatment
Central sleep apnea (CSA) is characterized by a lack of drive to breathe during sleep,
resulting in repetitive periods of insufficient ventilation and compromised gas exchange. These …
resulting in repetitive periods of insufficient ventilation and compromised gas exchange. These …
Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy
DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to understand
these reasons, easily identify them in individual patients, and develop therapies that …
these reasons, easily identify them in individual patients, and develop therapies that …
Obstructive sleep apnea: current perspectives
…, SG Carter, JC Carberry, DJ Eckert - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences of …
safety, and economic consequences. On an individual level, the causes and consequences of …
Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold
Recent insights into sleep apnoea pathogenesis reveal that a low respiratory arousal
threshold (awaken easily) is important for many patients. As most patients experience stable …
threshold (awaken easily) is important for many patients. As most patients experience stable …
Treating obstructive sleep apnea with hypoglossal nerve stimulation
…, CE Palme, S Robinson, GS Goding, DJ Eckert… - Sleep, 2011 - academic.oup.com
Background: Reduced upper airway muscle activity during sleep is fundamental to obstructive
sleep apnea (OSA) pathogenesis. Hypoglossal nerve stimulation (HGNS) counteracts this …
sleep apnea (OSA) pathogenesis. Hypoglossal nerve stimulation (HGNS) counteracts this …
Arousal from sleep: implications for obstructive sleep apnea pathogenesis and treatment
DJ Eckert, MK Younes - Journal of Applied Physiology, 2014 - journals.physiology.org
Historically, brief awakenings from sleep (cortical arousals) have been assumed to be vitally
important in restoring airflow and blood-gas disturbances at the end of obstructive sleep …
important in restoring airflow and blood-gas disturbances at the end of obstructive sleep …
Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea
Key points • Obstructive sleep apnoea (OSA) probably results from the interaction of key
pathophysiological traits including compromised pharyngeal anatomy, inadequate upper‐…
pathophysiological traits including compromised pharyngeal anatomy, inadequate upper‐…
A method for measuring and modeling the physiological traits causing obstructive sleep apnea
There is not a clinically available technique for measuring the physiological traits causing
obstructive sleep apnea (OSA). Therefore, it is often difficult to determine why an individual has …
obstructive sleep apnea (OSA). Therefore, it is often difficult to determine why an individual has …