[HTML][HTML] Epigallocatechin-3-gallate (EGCG) for clinical trials: more pitfalls than promises?

D Mereles, W Hunstein - International journal of molecular sciences, 2011 - mdpi.com
… Both components B and D contribute to the exertion of biological activities related to the
cell-surface 67 kDa laminin receptor [13,14]. EGCG molecular docking fractions for amyloid …

Biomarker changes after strenuous exercise can mimic pulmonary embolism and cardiac injury—a metaanalysis of 45 studies

…, E Kayvanpour, L Frankenstein, D Mereles… - Clinical …, 2015 - academic.oup.com
… Plasma d-dimer is used clinically to exclude venous thromboembolism with a high negative
… Likewise, the negative predictive values of natriuretic peptides and d-dimers are hampered …

Definition, clinical classification and initial diagnosis of pulmonary hypertension: Updated recommendations from the Cologne Consensus Conference 2018

…, I Kruck, AE Lammers, D Mereles… - International journal of …, 2018 - Elsevier
In the summer of 2016, delegates from the German Society of Cardiology (DGK), the German
Respiratory Society (DGP), and the German Society of Pediatric Cardiology (DGPK) met in …

Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension

D Mereles, N Ehlken, S Kreuscher, S Ghofrani… - Circulation, 2006 - Am Heart Assoc
… Three patients who were on oxygen therapy 16 h/d before inclusion in this study kept the …
channel blocker and received amlodipine 15 mg/d; the other patients received calcium channel …

Atlas of the clinical genetics of human dilated cardiomyopathy

…, DT Li, A Amr, P Ehlermann, D Mereles… - European heart …, 2015 - academic.oup.com
Aim Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until
now technological limitations have hindered elucidation of the contribution of all clinically …

Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers

SJ Buss, M Emami, D Mereles, G Korosoglou… - Journal of the American …, 2012 - jacc.org
Objectives : The aim of the study was to determine whether longitudinal left ventricular (LV)
function provides prognostic information in a large cohort of patients with systemic light-chain …

Alterations in cardiac DNA methylation in human dilated cardiomyopathy

…, JH Schultz, A Dösch, D Mereles… - EMBO molecular …, 2013 - embopress.org
Dilated cardiomyopathies (DCM) show remarkable variability in their age of onset, phenotypic
presentation, and clinical course. Hence, disease mechanisms must exist that modify the …

Stress Doppler echocardiography in relatives of patients with idiopathic and familial pulmonary arterial hypertension: results of a multicenter European analysis of …

…, J Kober, R Koehler, RD Machado, D Mereles… - Circulation, 2009 - Am Heart Assoc
Background— This large, prospective, multicentric study was performed to analyze the
distribution of tricuspid regurgitation velocity (TRV) values during exercise and hypoxia in …

Stress Doppler echocardiography for identification of susceptibility to high altitude pulmonary edema

E Grünig, D Mereles, W Hildebrandt… - Journal of the American …, 2000 - jacc.org
OBJECTIVE This prospective single-blinded study was performed to quantitate noninvasive
pulmonary artery systolic pressure (PASP) responses to prolonged acute hypoxia and …

Abnormal pulmonary artery pressure response in asymptomatic carriers of primary pulmonary hypertension gene

E Grünig, B Janssen, D Mereles, U Barth, MM Borst… - Circulation, 2000 - Am Heart Assoc
Background—Familial primary pulmonary hypertension (PPH) is an autosomal-dominant
inherited disease with incomplete penetrance and poor prognosis. This study was performed to …