Members of the genus Pseudomonas inhabit a wide variety of environments, which is
reflected in their versatile metabolic capacity and broad potential for adaptation to fluctuating …

Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …

Background Pseudomonas aeruginosa colonisation of the airways of patients with cystic
fibrosis (CF) is associated with considerable respiratory morbidity. Although segregation of …

Pseudomonas aeruginosa isolates have a highly conserved core genome representing up
to 90% of the total genomic sequence with additional variable accessory genes, many of …

Rationale: Pseudomonas aeruginosa isolates from chronic cystic fibrosis lung infections
display multiple phenotypes indicating extensive population diversity. Objectives: We aimed to …

The Liverpool epidemic strain (LES) of Pseudomonas aeruginosa is a transmissible aggressive
pathogen of cystic fibrosis (CF) patients. We compared transcriptome profiles of two LES …

Objective Colonic mucosa-associated Escherichia coli are increased in Crohn's disease (CD)
and colorectal cancer (CRC). They variously haemagglutinate, invade epithelial cell lines, …

Studies on cultured cells and in infection models have shown that cell density-dependent
quorum-sensing (QS) controls many of the known virulence factors of Pseudomonas …

Campylobacter species are the most common cause of bacterial gastroenteritis, with C.
jejuni responsible for the majority of these cases. Although it is clear that livestock, and …

There is growing concern about the relevance of in vitro antimicrobial susceptibility tests
when applied to isolates of P. aeruginosa from cystic fibrosis (CF) patients. Existing methods …