TAM receptors (Tyro3, Axl, and Mer) belong to a family of receptor tyrosine kinases that have
important effects on hemostasis and inflammation. Also, they affect cell proliferation, survival…

Platelets are small circulating anucleate cells that are of crucial importance in haemostasis.
Over the last decade, it has become increasingly clear that platelets play an important role in …

Asthma is a chronic airway disease characterized by paroxysmal airflow obstruction evoked
by irritative stimuli on a background of allergic lung inflammation. Currently, there is no cure …

Members of the Toll-like receptor (TLR) family probably play a fundamental role in pathogen
recognition and activation of innate immunity. The present study used a systematic …

Ischemia followed by reperfusion leads to severe organ injury and dysfunction. Inflammation
is considered to be the most important cause of tissue injury in organs subjected to ischemia…

The reported requirement of functional Toll-like receptor (TLR) 4 for resistance to Gram-negative
pyelonephritis prompted us to localize the expression of TLR2 and TLR4 mRNA in the …

We have investigated the influence of alterations in plasma coagulation factor levels between
50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, …

Toll-like receptors (TLR) are crucial pattern recognition receptors in innate immunity. The
importance of TLR2 in host defense against Gram-positive bacteria has been suggested by the …

Chylomicrons have been shown to protect against endotoxin-induced lethality. LPS-binding
protein (LBP) is involved in the inactivation of bacterial toxin by lipoproteins. The current …

Thrombocytopenia is a common finding in sepsis and associated with a worse outcome. We
used a mouse model of pneumonia-derived sepsis caused by the human pathogen …