User profiles for Cornelia Blume

Cornelia Blume

- Verified email at iftc.uni-hannover.de - Cited by 3192

Cornelia Blume

- Verified email at soton.ac.uk - Cited by 1369

[HTML][HTML] A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection

C Blume, CL Jackson, CM Spalluto, J Legebeke… - Nature …, 2021 - nature.com
Angiotensin-converting enzyme 2 (ACE2) is the main entry point in airway epithelial cells for
SARS-CoV-2. ACE2 binding to the SARS-CoV-2 protein spike triggers viral fusion with the …

[HTML][HTML] Signs of immunosenescence correlate with poor outcome of mRNA COVID-19 vaccination in older adults

MÁ Palacios-Pedrero, JM Jansen, C Blume… - Nature Aging, 2022 - nature.com
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing COVID-19 hospitalization and fatal outcome. However, several studies …

In vitro and ex vivo models of human asthma

C Blume, DE Davies - European journal of pharmaceutics and …, 2013 - Elsevier
Asthma is an inflammatory disorder of the conducting airways which undergo distinct
structural and functional changes leading to non-specific bronchial hyperresponsiveness (BHR) …

[HTML][HTML] Autoimmunity in CD73/Ecto-5′-nucleotidase deficient mice induces renal injury

C Blume, A Felix, N Shushakova, F Gueler, CS Falk… - PloS one, 2012 - journals.plos.org
Extracellular adenosine formed by 5′-ectonucleotidase (CD73) is involved in tubulo-glomerular
feedback in the kidney but is also known to be an important immune modulator. Since …

Cerivastatin inhibits proliferation of interleukin-1β-induced rat mesangial cells by enhanced formation of nitric oxide

C Blume, D Sabuda-Widemann, J Pfeilschifter… - European journal of …, 2004 - Elsevier
The antiproliferative effect of statins on mesangial cells could represent a new therapeutic
approach in glomerulonephritis. We studied in rat mesangial cells whether the antiproliferative …

Hydrogels for 3D mammalian cell culture: a starting guide for laboratory practice

F Ruedinger, A Lavrentieva, C Blume… - Applied microbiology …, 2015 - Springer
Hydrogels have become one of the most popular platforms for three-dimensional (3D) cultivation
of mammalian cells. The enormous versatility of hydrogel materials makes it possible to …

Increase of infectious complications in ABO-incompatible kidney transplant recipients—a single centre experience

A Habicht, V Bröker, C Blume… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. Due to the shortage of deceased donors ABO-incompatible (ABOi) living kidney
transplantation has become a popular alternative to deceased kidney transplantation. In …

Pollen exposure weakens innate defense against respiratory viruses

S Gilles, C Blume, M Wimmer, A Damialis… - Allergy, 2020 - Wiley Online Library
Background Hundreds of plant species release their pollen into the air every year during
early spring. During that period, pollen allergic as well as non‐allergic patients frequently …

[HTML][HTML] TNF-α–mediated bronchial barrier disruption and regulation by src-family kinase activation

…, E Wilkinson, E Martin, NP Jayasekera, C Blume… - Journal of Allergy and …, 2013 - Elsevier
Background Because TNF-α is increased in severe asthma, we hypothesized that TNF-α
contributes to barrier dysfunction and cell activation in bronchial epithelial cells. We further …

Epithelial function and dysfunction in asthma

M Loxham, DE Davies, C Blume - Clinical & Experimental …, 2014 - Wiley Online Library
Asthma was previously defined as an allergic Th2‐mediated inflammatory immune disorder.
Recently, this paradigm has been challenged because not all pathological changes …