Background Individuals with cancer, particularly those who are receiving systemic anticancer
treatments, have been postulated to be at increased risk of mortality from COVID-19. This …

Background Patients with cancer are purported to have poor COVID-19 outcomes. However,
cancer is a heterogeneous group of diseases, encompassing a spectrum of tumour …

Rationale: Obstructive sleep apnea (OSA) is associated with systemic hypertension. Either
overnight intermittent hypoxia, or the recurrent arousals that occur in OSA, could cause the …

The SARS-CoV-2 can lead to severe illness with COVID-19. Outcomes of patients requiring
mechanical ventilation are poor. Awake proning in COVID-19 improves oxygenation, but on …

Obstructive sleep apnoea (OSA) is increasing in prevalence due to rising obesity. While OSA
is a disorder primarily of the upper airway during sleep, its pathophysiological impact on …

One night of a sleep study is the standard for diagnosis and exclusion of obstructive sleep
apnea. Single testing requires high sensitivity of the test method and a stable disease of …

The sleep‐wake cycle in Parkinson's Disease (PD) is profoundly disrupted, but less is known
about circadian rhythm in PD and its relationship to other important clinical features. This …

Background The evidence base for the treatment of mild obstructive sleep apnoea is limited
and definitions of disease severity vary. The MERGE trial investigated the clinical …

Obstructive sleep apnoea (OSA) is a common disorder and is associated with cardiovascular
disease. Continuous positive airway pressure (CPAP), whilst reducing blood pressure, has …

Introduction Acute exacerbations of COPD (AECOPD) complicated by acute (acidaemic)
hypercapnic respiratory failure (AHRF) requiring ventilation are common. When applied …