Background Shortening the course of treatment for tuberculosis would be a major improvement
for case management and disease control. This phase 3 trial assessed the efficacy and …

Background Tuberculosis in children is increasingly recognised as an important component
of the global tuberculosis burden, with an estimated 1 million cases in 2015. Although …

OBJECTIVE: To present a global update of drug-resistant tuberculosis (TB) and explore trends
in 1994-2010. METHODS: Data on drug resistance among new and previously treated TB …

Despite the availability of effective chemotherapy, tuberculosis (TB) killed 1.3 million people
in 2012. Alongside HIV, it remains a top cause of death from an infectious disease. Global …

Background After infection with Mycobacterium tuberculosis, children are at an increased
risk of progression to tuberculosis disease; a condition that can be challenging to diagnose. …

Objective and Methods In many countries, national tuberculosis (TB) prevalence surveys
are the only way to reliably measure the burden of TB disease and monitor trends. They can …

Background The Stop TB Partnership target for tuberculosis is to have reduced the
prevalence of tuberculosis by 50% comparing 2015 to 1990. This target is challenging as few …

Historical data show that the risk of tuberculosis increases dramatically during adolescence,
and young people face unique challenges in terms of case detection and effective treatment…

Tuberculosis affected an estimated 8.8 million people and caused 1.4 million deaths globally
in 2010, including a half-million women and at least 64 000 children. It also results in …

Background In several settings, women with suspected tuberculosis are less likely to test
smear positive than are men. Submission of poor-quality sputum specimens by women might …