Both occupational and environmental exposure to particles is associated with an increased
risk of lung cancer. Particles are thought to impact on genotoxicity as well as on cell …

Nanotechnology makes use of the special surface properties of extremely small particles. In
this rapidly growing field, many different materials are produced for a multitude of diverse …

Inhaled ultrafine particles show considerably stronger pulmonary inflammatory effects when
tested at equal mass dose with their fine counterparts. However, the responsible …

Poorly soluble particles of low toxicity (PSP), such as CB, TiO 2 and coal mine dust, have
been demonstrated to cause lung cancer in rodents, being most pronounced in rats. Adequate …

The use of engineered nanoparticles in the food sector is anticipated to increase dramatically,
whereas their potential hazards for the gastrointestinal tract are still largely unknown. We …

Titanium dioxide has a long-standing use as a food additive. Micrometric powders are, eg,
applied as whiteners in confectionary or dairy products. Possible hazards of ingested …

Infection of cattle with the bovine leukemia virus (BLV) results in a strong permanent antibody
response to the BLV antigens some weeks after infection. However, cattle may carry …

In view of the steadily increasing use of zinc oxide nanoparticles in various industrial and
consumer applications, toxicological investigations to evaluate their safety are highly justified. …

Rationale: Inflammatory reactions of the airways induced by nanoparticles of occupational
and environmental origin contribute to organ-specific and systemic human diseases. Because …

Rationale Mineral particles in the lung cause inflammation and silicosis. In myeloid and
bronchial epithelial cells the inflammasome plays a role in responses to crystalline silica. …