[HTML][HTML] Primary immunodeficiency diseases: an update on the classification from the International Union of Immunological Societies Expert Committee for Primary …
C Picard, W Al-Herz, A Bousfiha, JL Casanova… - Journal of clinical …, 2015 - Springer
We report the updated classification of primary immunodeficiencies compiled by the Primary
Immunodeficiency Expert Committee (PID EC) of the International Union of Immunological …
Immunodeficiency Expert Committee (PID EC) of the International Union of Immunological …
[PDF][PDF] Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors
…, B Senechal, A Puel, SK Biswas, D Moshous, C Picard… - Immunity, 2010 - cell.com
Monocytes are effectors of the inflammatory response to microbes. Human CD14 +
monocytes specialize in phagocytosis and production of reactive oxygen species and secrete …
monocytes specialize in phagocytosis and production of reactive oxygen species and secrete …
Pyogenic bacterial infections in humans with IRAK-4 deficiency
C Picard, A Puel, M Bonnet, CL Ku, J Bustamante… - Science, 2003 - science.org
Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share
an intracytoplasmic Toll–IL-1 receptor (TIR) domain, which mediates recruitment of the …
an intracytoplasmic Toll–IL-1 receptor (TIR) domain, which mediates recruitment of the …
TLR3 deficiency in patients with herpes simplex encephalitis
…, V Sancho-Shimizu, L Lorenzo, A Puel, C Picard… - science, 2007 - science.org
Some Toll and Toll-like receptors (TLRs) provide immunity to experimental infections in
animal models, but their contribution to host defense in natural ecosystems is unknown. We …
animal models, but their contribution to host defense in natural ecosystems is unknown. We …
[HTML][HTML] Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee
…, T Morio, HD Ochs, E Oksenhendler, C Picard… - Journal of clinical …, 2020 - Springer
We report the updated classification of Inborn Errors of Immunity/Primary Immunodeficiencies,
compiled by the International Union of Immunological Societies Expert Committee. This …
compiled by the International Union of Immunological Societies Expert Committee. This …
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity
…, S Al-Muhsen, M Galicchio, L Abel, C Picard… - Science, 2011 - science.org
Chronic mucocutaneous candidiasis disease (CMCD) is characterized by recurrent or persistent
infections of the skin, nails, and oral and genital mucosae caused by Candida albicans …
infections of the skin, nails, and oral and genital mucosae caused by Candida albicans …
[HTML][HTML] International union of immunological societies: 2017 primary immunodeficiency diseases committee report on inborn errors of immunity
C Picard, H Bobby Gaspar, W Al-Herz… - Journal of clinical …, 2018 - Springer
Beginning in 1970, a committee was constituted under the auspices of the World Health
Organization (WHO) to catalog primary immunodeficiencies. Twenty years later, the International …
Organization (WHO) to catalog primary immunodeficiencies. Twenty years later, the International …
Herpes simplex virus encephalitis in human UNC-93B deficiency
…, E Jouanguy, A Puel, K Yang, A Alcais, C Picard… - Science, 2006 - science.org
Herpes simplex virus-1 (HSV-1) encephalitis (HSE) is the most common form of sporadic viral
encephalitis in western countries. Its pathogenesis remains unclear, as it affects otherwise …
encephalitis in western countries. Its pathogenesis remains unclear, as it affects otherwise …
Pyogenic bacterial infections in humans with MyD88 deficiency
H Von Bernuth, C Picard, Z Jin, R Pankla, H Xiao… - Science, 2008 - science.org
MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1
receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to a broad range of …
receptors (IL-1Rs). MyD88 deficiency in mice leads to susceptibility to a broad range of …
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis
Chronic mucocutaneous candidiasis disease (CMCD) may be caused by autosomal dominant
(AD) IL-17F deficiency or autosomal recessive (AR) IL-17RA deficiency. Here, using whole…
(AD) IL-17F deficiency or autosomal recessive (AR) IL-17RA deficiency. Here, using whole…