The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting,
and appraisal. However, trial protocols and existing protocol guidelines vary greatly in …

Purpose To determine whether adding shear-wave (SW) elastographic features could improve
accuracy of ultrasonographic (US) assessment of breast masses. Materials and Methods …

80 reports of randomised clinical trials in four leading general medical journals were reviewed.
The reporting of the methodology of randomisation was inadequate. In 30% of trials there …

Background Diet influences the prevalence of coronary heart disease (CHD). Insulin
sensitivity and concentrations of HDL cholesterol, two metabolic predictors of CHD, are also …

In a regional Health District with a population of 198900, 357 patients with 424 ulcerated legs
were documented, an overall prevalence of 0.18 per cent. The prevalence of ulceration in …

… Medica; Medical advisory board of Philips Ultrasound; C Dore received consulting fees from
SuperSonic Imagine. Employees of SuperSonic Imagine. … Caroline J Doré … Caroline J Doré …

Objective Juvenile idiopathic arthritis (JIA) can persist through adolescence and adulthood,
resulting in significant disability. The use of low‐dose oral methotrexate (MTX) for persistent …

Background: Hepatic steatosis is associated with obesity and type II diabetes. Proton magnetic
resonance spectroscopy ( 1 H MRS) is a non-invasive method for measurement of tissue …

Background Adjustment for prognostic covariates can lead to increased power in the analysis
of randomized trials. However, adjusted analyses are not often performed in practice. …

Colony-forming units of Mycobacterium tuberculosis in sputum were counted at 2-day intervals
in 100 patients treated with 22 regimens of isoniazid, rifampin, pyrazinamide, ethambutol, …