User profiles for C. M. van Duijn
Cornelia M van DuijnUniversity of Oxford Verified email at ndph.ox.ac.uk Cited by 246274 |
ACE Polymorphisms
…, BA Oostra, A Isaacs, CM Van Duijn… - Circulation …, 2006 - Am Heart Assoc
Angiotensin converting enzyme (ACE) plays an essential role in two physiological systems,
one leading to the production of angiotensin II and the other to the degradation of bradykinin. …
one leading to the production of angiotensin II and the other to the degradation of bradykinin. …
Genome-based prediction of common diseases: advances and prospects
ACJW Janssens, CM van Duijn - Human molecular genetics, 2008 - academic.oup.com
… van Duijn … van Duijn … van Duijn, Genome-based prediction of common diseases: advances
and prospects, Human Molecular Genetics, Volume 17, Issue R2, 15 October 2008, Pages …
and prospects, Human Molecular Genetics, Volume 17, Issue R2, 15 October 2008, Pages …
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …
the world and has received considerable attention regarding health risks and benefits. We …
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis
Objective. —To examine more closely the association between apolipoprotein E (APOE)
genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and …
genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and …
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
…, JC van Swieten, A Brice, G Meco, CM van Duijn… - Science, 2003 - science.org
The DJ-1 gene encodes a ubiquitous, highly conserved protein. Here, we show that DJ-1
mutations are associated with PARK7, a monogenic form of human parkinsonism. The function …
mutations are associated with PARK7, a monogenic form of human parkinsonism. The function …
GenABEL: an R library for genome-wide association analysis
Here we describe an R library for genome-wide association (GWA) analysis. It implements
effective storage and handling of GWA data, fast procedures for genetic data quality control, …
effective storage and handling of GWA data, fast procedures for genetic data quality control, …
[HTML][HTML] Variant of TREM2 Associated with the Risk of Alzheimer's Disease
…, A Hofman, MA Ikram, CM van Duijn… - … England Journal of …, 2013 - Mass Medical Soc
Background Sequence variants, including the ε4 allele of apolipoprotein E, have been
associated with the risk of the common late-onset form of Alzheimer's disease. Few rare variants …
associated with the risk of the common late-onset form of Alzheimer's disease. Few rare variants …
Genome-wide association study of blood pressure and hypertension
Blood pressure is a major cardiovascular disease risk factor. To date, few variants associated
with interindividual blood pressure variation have been identified and replicated. Here we …
with interindividual blood pressure variation have been identified and replicated. Here we …
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
…, CM van Duijn… - Nature …, 2011 - nature.com
We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of >12 million variants, …
elderly, with limited therapeutic options. Here we report on a study of >12 million variants, …