Mutation and horizontal gene transfer (HGT) continually give rise to new bacterial genotypes.
Infrequently, such new bacterial genotypes establish and spread in the larger population …

During the past 10 years, multidrug-resistant Gram-negative Enterobacteriaceae have become
a substantial challenge to infection control. It has been suggested by clinicians that the …

The development and spread of antibiotic resistance in bacteria is a universal threat to both
humans and animals that is generally not preventable but can nevertheless be controlled, …

The tomato Cf-9 gene confers resistance to infection by races of the fungus Cladosporium
fulvum that carry the avirulence gene Avr9. The Cf-9 gene was isolated by transposon tagging …

… Thomas Christophe Thomas obtained his PhD degree in 2002 working under the supervision
of Professor Süss-Fink. He then joined Professor Coates’ group at Cornell University as a …

Antibiotics have saved countless lives and enabled the development of modern medicine over
the past 70 years. However, it is clear that the success of antibiotics might only have been …

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi
and plants are known to be encoded in biosynthetic gene clusters. Information about these …

In plants, resistance to pathogens is frequently determined by dominant resistance genes,
whose products are proposed to recognize pathogen-encoded avirulence gene (Avr) products…

Tomato Cf genes confer resistance to C. fulvum, reside in complex loci carrying multiple
genes, and encode predicted membrane-bound proteins with extracytoplasmic leucine-rich …

… Jagura-Burdzy & CM Thomas, unpublished results) and by genetic analysis (Theophilus
elf al., 1985; Young et ol., 1985). A common feature is the clustering of binding sites. This can …