User profiles for C-H. Tsai

Chin-Ho Tsai

National Dong Hwa University
Verified email at gms.ndhu.edu.tw
Cited by 2021

Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

…, HY Huang, WC Wang, CH Liu, MK Lu, CH Lu… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4·5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Lactate modulation of immune responses in inflammatory versus tumour microenvironments

M Certo, CH Tsai, V Pucino, PC Ho… - Nature Reviews …, 2021 - nature.com
… As voltage-dependent anion channel-dependent binding of HK2 to the outer membrane
of mitochondria promotes cell survival 30 , our findings could explain the persistence and …

Metabolic communication in the tumour–immune microenvironment

KC Kao, S Vilbois, CH Tsai, PC Ho - Nature Cell Biology, 2022 - nature.com
The metabolically hostile tumour microenvironment imposes barriers to tumour-infiltrating
immune cells and impedes durable clinical remission following immunotherapy. Metabolic …

[HTML][HTML] IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

…, JY Yang, AA Sahin, GN Hortobagyi, FJ Tsai, CH Tsai… - Cell, 2007 - cell.com
TNFα has recently emerged as a regulator linking inflammation to cancer pathogenesis, but
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated. …

Crust–mantle interaction induced by deep subduction of the continental crust: geochemical and Sr–Nd isotopic evidence from post-collisional mafic–ultramafic …

B Jahn, F Wu, CH Lo, CH Tsai - Chemical geology, 1999 - Elsevier
Interaction of deeply subducted continental blocks with the upper mantle peridotite is a
likely process, but it has never been demonstrated. New geochemical and isotope tracer …

[HTML][HTML] Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke

…, S Curtze, HM Dewey, F Miteff, CH Tsai… - … England Journal of …, 2019 - Mass Medical Soc
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is generally
limited to within 4.5 hours after the onset of symptoms. Some trials have suggested that …

Securing web application code by static analysis and runtime protection

YW Huang, F Yu, C Hang, CH Tsai, DT Lee… - Proceedings of the 13th …, 2004 - dl.acm.org
Security remains a major roadblock to universal acceptance of the Web for many kinds of
transactions, especially since the recent sharp increase in remotely exploitable vulnerabilities …

Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants

HC Lin, BH Su, AC Chen, TW Lin, CH Tsai, TF Yeh… - …, 2005 - publications.aap.org
Objective. We evaluated the efficacy of probiotics in reducing the incidence and severity of
necrotizing enterocolitis (NEC) in very low birth weight (VLBW) infants. Patients and Methods. …

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

…, X Cheng, KJ Chang, CD Hsiao, FJ Tsai, CH Tsai… - Nature cell …, 2008 - nature.com
The RAS–ERK pathway is known to play a pivotal role in differentiation, proliferation and
tumour progression. Here, we show that Erk downregulates Forkhead box O 3a (FOXO3a) by …

[PDF][PDF] Erk associates with and primes GSK-3β for its inactivation resulting in upregulation of β-catenin

…, Z Li, RC Bargou, J Qin, CC Lai, FJ Tsai, CH Tsai… - Molecular cell, 2005 - cell.com
β-catenin is upregulated in many human cancers and considered to be an oncogene.
Hepatocellular carcinoma (HCC) is one of the most prevalent human malignancies, and …