Transforming growth factor-beta (TGF-beta) is a cytokine that promotes extracellular matrix
accumulation and inhibits matrix degradation. Although the natural course of sarcoidosis is …

… FcεRI α-chain expression evaluated by using immunofluorescence on BMs from an NAS (A
and B) or from an AAP (C and D) incubated for 24 hours with medium alone (A and C) or with …

BACKGROUND: Monocytic cells and alveolar macrophages (AMs) are activated in patients
with asthma, producing inflammatory cytokines. This occurs despite a T H 2 environment that …

The polarization of the immune response toward a Th2 or a Th1 profile can be mediated by
dendritic cells (DCs) following antigen presentation and interaction with T cells. …

… Latent TGF-β in cell-free BALF was activated by heating at 80C in the presence of 0.5 mmol/L
phenylmethyl sulfonyl fluoride and 5 μmol/L ilomastat. Exogenously added active TGF-β (…

… En particulier, il existe un plus grand nombre d’eosinophiles, et notamment d’eosinophiles
actives, dans les parois des voies aeriennes de gros et moyen calibre [2]. Par ailleurs, une …

… , Palo Alto, CA) coated tissue culture dishes at 37 C in a humidified atmosphere of 5% CO2,
and … Frozen cells were gently thawed at 37 C and resuspended in LHC9/RPMI 1640 directly …

Human Toll-like receptor 4 (TLR4) has recently been identified, and it has been shown to be
the main protein involved in recognizing gram-negative bacteria. We examined the …

Sarcoidosis, a multisystem granulomatous disorder, has historically been classified as Th1-driven
disease. However, increasing data demonstrate a key role of Th17-cell plasticity in …

… incubated for 30 min in the dark at 4C. Then the cells were washed twice with PBS, suspended
in 0.4 ml of PBS with 1% paraformaldehyde, stored at 4C, and analyzed within 24 h. The …