DC-SIGN Is the Major Mycobacterium tuberculosis Receptor on Human Dendritic Cells

…, JC Gluckman, PH Lagrange, B Gicquel… - The Journal of …, 2003 - rupress.org
Early interactions between lung dendritic cells (LDCs) and Mycobacterium tuberculosis, the
etiological agent of tuberculosis, are thought to be critical for mounting a protective anti-…

Variable human minisatellite‐like regions in the Mycobacterium tuberculosis genome

…, S Lesjean, V Vincent, B Gicquel… - Molecular …, 2000 - Wiley Online Library
Mycobacterial interspersed repetitive units (MIRUs) are 40–100 bp DNA elements often found
as tandem repeats and dispersed in intergenic regions of the Mycobacterium tuberculosis …

Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature‐tagged transposon mutagenesis

…, D Ensergueix, E Perez, B Gicquel… - Molecular …, 1999 - Wiley Online Library
Tuberculosis remains the greatest cause of death worldwide due to a single pathogen. In
order to identify the genes required for the pathogenicity of Mycobacterium tuberculosis, a …

A Mycobacterium tuberculosis operon encoding ESAT= 6 and a novel low-molecular-mass culture filtrate protein (CFP-10)

…, I Rosenkrands, P Andersen, B Gicquel - …, 1998 - microbiologyresearch.org
The early secreted antigenic target 6 kDa protein (ESAT-6) is a potent T-cell protein antigen
synthesized by Mycobacterium tuberculosis. Its corresponding gene (esat-6) is located in …

Mycobacterium abscessus: a new antibiotic nightmare

…, JM Reyrat, A Murray, B Gicquel - Journal of …, 2012 - academic.oup.com
The intrinsic and acquired resistance of Mycobacterium abscessus to commonly used
antibiotics limits the chemotherapeutic options for infections caused by these mycobacteria. …

High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology

…, M Gilbert, V Vincent, B Gicquel… - Proceedings of the …, 2001 - National Acad Sciences
The worldwide threat of tuberculosis to human health emphasizes the need to develop
novel approaches to a global epidemiological surveillance. The current standard for …

Characterization of a Mycobacterium tuberculosis insertion sequence, IS6110, and its application in diagnosis

…, S Nguyen, JL Guesdon, B Gicquel - Journal of clinical …, 1990 - Am Soc Microbiol
An insertion sequence-like element, IS6110, was isolated from a Mycobacterium tuberculosis
cosmid library as a repetitive sequence. IS6110 shows similarities with elements of the IS3 …

IS6110, an IS-like element of Mycobacterium tuberculosis complex.

…, JT Crawford, JH Bates, B Gicquel… - Nucleic acids …, 1990 - ncbi.nlm.nih.gov
Mobile genetic elements are useful genetic tools. They have been found in most organisms
which have been examined (for recent reviews see 1). IS900 was isolated from M. …

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

…, JM Reyrat, WR Jacobs Jr, B Gicquel… - Proceedings of the …, 1997 - National Acad Sciences
A better understanding of Mycobacterium tuberculosis virulence mechanisms is highly
dependent on the design of efficient mutagenesis systems. A system enabling the positive …

[HTML][HTML] Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

…, C Bouchier, M Tichit, O Neyrolles, B Gicquel… - PLoS …, 2009 - journals.plos.org
Infectious diseases have been paramount among the threats to health and survival throughout
human evolutionary history. Natural selection is therefore expected to act strongly on host …