Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte …
Macrolide antibiotics possess immunomodulatory/anti-inflammatory properties. These
properties are considered fundamental for the efficacy of macrolide antibiotics in the treatment of …
properties are considered fundamental for the efficacy of macrolide antibiotics in the treatment of …
Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice
VI Tkalčević, B Bošnjak, B Hrvačić, M Bosnar… - European journal of …, 2006 - Elsevier
Macrolide antibacterials inhibit the production of various cytokines and the migration of
inflammatory cells. These anti-inflammatory actions of macrolides may be beneficial in …
inflammatory cells. These anti-inflammatory actions of macrolides may be beneficial in …
Azithromycin inhibits macrophage interleukin-1β production through inhibition of activator protein-1 in lipopolysaccharide-induced murine pulmonary neutrophilia
…, G Ergović, N Marjanović, I Pašalić, B Hrvačić… - International …, 2011 - Elsevier
Macrolide antibiotics, including azithromycin, also possess anti-inflammatory properties.
However, the molecular mechanism(s) of activity as well as the target cells for their action have …
However, the molecular mechanism(s) of activity as well as the target cells for their action have …
[HTML][HTML] Claudins: beyond tight junctions in human IBD and murine models
…, A Petrinić Grba, B Hrvačić… - Frontiers in …, 2021 - frontiersin.org
Claudins are transmembrane proteins constituting one of three tight junction protein families.
In patients with inflammatory bowel disease (IBD), disease activity–dependent changes in …
In patients with inflammatory bowel disease (IBD), disease activity–dependent changes in …
N′-Substituted-2′-O,3′-N-carbonimidoyl Bridged Macrolides: Novel Anti-inflammatory Macrolides without Antimicrobial Activity
…, Z Marušić Ištuk, S Kapić, B Hrvačić… - Journal of medicinal …, 2012 - ACS Publications
Macrolide antibiotics, like erythromycin, clarithromycin, and azithromycin, possess anti-inflammatory
properties. These properties are considered fundamental to the efficacy of these …
properties. These properties are considered fundamental to the efficacy of these …
Clarithromycin suppresses airway hyperresponsiveness and inflammation in mouse models of asthma
B Hrvačić, B Bošnjak, M Bosnar, Ž Ferenčić… - European journal of …, 2009 - Elsevier
Macrolide antibiotics, a class of potent antimicrobials, also possess immunomodulatory/anti-inflammatory
properties. These properties are considered fundamental for the efficacy of …
properties. These properties are considered fundamental for the efficacy of …
Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5 …
…, P Mollat, M Lamers, M Auberval, B Hrvacic… - 2017 - ACS Publications
Autotaxin is a circulating enzyme with a major role in the production of lysophosphatic acid (LPA)
species in blood. A role for the autotaxin/LPA axis has been suggested in many …
species in blood. A role for the autotaxin/LPA axis has been suggested in many …
Porphyrins as new endogenous anti-inflammatory agents
A series of porphyrins, tetrapyrrole natural organic compounds, are evaluated here as
endogenous anti-inflammatory agents. They directly inhibit the activity of Fyn, a non-receptor Src-…
endogenous anti-inflammatory agents. They directly inhibit the activity of Fyn, a non-receptor Src-…
Synthesis and anti-inflammatory activity of novel furochromenes
A series of variously substituted furochromenes, hemiacetals 2, acetals 3, and rearranged
compounds 4, were synthesized from variously substituted 4-hydroxycoumarins and …
compounds 4, were synthesized from variously substituted 4-hydroxycoumarins and …
Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma
Purpose We have assessed the use of an ultrasonic nebulization system (UNS), composed
of ultrasonic nebulizer and diffusion dryer filled with charcoal, for the effective delivery of …
of ultrasonic nebulizer and diffusion dryer filled with charcoal, for the effective delivery of …