High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation
…, H Diedrich, B Güldenzoph… - Blood, The Journal …, 2011 - ashpublications.org
Nelarabine, a purine analog with T-cell specific action, has been approved for relapsed/refractory
T-cell acute lymphoblastic leukemia/lymphoma (ALL/LBL). This is a report of a single-…
T-cell acute lymphoblastic leukemia/lymphoma (ALL/LBL). This is a report of a single-…
CD154/CD40-mediated expression of CD154 in endothelial cells: consequences for endothelial cell–monocyte interaction
AH Wagner, B Güldenzoph… - … , and vascular biology, 2004 - Am Heart Assoc
Objective— CD40 ligand (CD154) expressed on activated T helper cells is a key costimulatory
molecule for antigen-presenting cells expressing the corresponding receptor CD40. …
molecule for antigen-presenting cells expressing the corresponding receptor CD40. …
3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells
AH Wagner, M Gebauer, B Güldenzoph… - … , and vascular biology, 2002 - Am Heart Assoc
Objective— 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins)
exert potent anti-inflammatory effects that are independent of their cholesterol-lowering …
exert potent anti-inflammatory effects that are independent of their cholesterol-lowering …
[HTML][HTML] Prognostic factors in nonsmall cell lung cancer: insights from the German CRISP registry
…, G Zaun, S Dörfel, B Güldenzoph… - European …, 2023 - Eur Respiratory Soc
Introduction Understanding prognosis, especially long-term outcome, in advanced nonsmall
cell lung cancer (NSCLC) is crucial to inform patients, guide treatment and plan supportive …
cell lung cancer (NSCLC) is crucial to inform patients, guide treatment and plan supportive …
Upregulation of glutathione peroxidase offsets stretch-induced proatherogenic gene expression in human endothelial cells
AH Wagner, O Kautz, K Fricke… - … , and vascular biology, 2009 - Am Heart Assoc
Objective— Localization of atherosclerotic plaques typically correlates with areas of
biomechanical strain where shear stress is decreased while stretch, thought to promote …
biomechanical strain where shear stress is decreased while stretch, thought to promote …
Intracellular ATP-binding cassette transporter A3 is expressed in lung cancer cells and modulates susceptibility to cisplatin and paclitaxel
…, R Waldmann-Beushausen, B Chapuy, B Güldenzoph… - Oncology, 2013 - karger.com
Patients with advanced-stage bronchial cancer benefit from systemic cytostatic therapy, in
particular from regimens integrating cisplatin and taxanes. However, eventual disease …
particular from regimens integrating cisplatin and taxanes. However, eventual disease …
Nuclear trapping through inhibition of exosomal export by indomethacin increases cytostatic efficacy of doxorubicin and pixantrone
R Koch, T Aung, D Vogel, B Chapuy, D Wenzel… - Clinical cancer …, 2016 - AACR
Purpose: Although R-CHOP–based immunochemotherapy cures significant proportions of
patients with aggressive B-cell lymphoma, tumor cell susceptibility to chemotherapy varies, …
patients with aggressive B-cell lymphoma, tumor cell susceptibility to chemotherapy varies, …
[HTML][HTML] Biomarker testing in non-small cell lung cancer in routine care: Analysis of the first 3,717 patients in the German prospective, observational, nation-wide …
F Griesinger, W Eberhardt, A Nusch, M Reiser… - Lung Cancer, 2021 - Elsevier
Objectives An increasing number of treatment-determining biomarkers has been identified
in non-small cell lung cancer (NSCLC) and molecular testing is recommended to enable …
in non-small cell lung cancer (NSCLC) and molecular testing is recommended to enable …
[HTML][HTML] KRAS G12C-mutated advanced non-small cell lung cancer: A real-world cohort from the German prospective, observational, nation-wide CRISP Registry (AIO …
M Sebastian, WEE Eberhardt, P Hoffknecht… - Lung Cancer, 2021 - Elsevier
Objectives After decades of unsuccessful efforts in inhibiting KRAS, promising clinical data
targeting the mutation subtype G12C emerge. Since little is known about outcome with …
targeting the mutation subtype G12C emerge. Since little is known about outcome with …
Patient‐reported outcomes in advanced NSCLC before and during the COVID‐19 pandemic: Real‐world data from the German prospective CRISP Registry (AIO‐TRK …
M Sebastian, WEE Eberhardt… - … Journal of Cancer, 2024 - Wiley Online Library
Patients with lung cancer under treatment have been associated with a high risk of COVID‐19
infection and potentially worse outcome, but real‐world data on patient‐reported …
infection and potentially worse outcome, but real‐world data on patient‐reported …