Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients
B Levänen, NR Bhakta, PT Paredes, R Barbeau… - Journal of Allergy and …, 2013 - Elsevier
BACKGROUND: Asthma is characterized by increased airway narrowing in response to
nonspecific stimuli. The disorder is influenced by both environmental and genetic factors. …
nonspecific stimuli. The disorder is influenced by both environmental and genetic factors. …
[HTML][HTML] The viral protein corona directs viral pathogenesis and amyloid aggregation
…, B Bestas, MJ Sobkowiak, B Levänen… - Nature …, 2019 - nature.com
Artificial nanoparticles accumulate a protein corona layer in biological fluids, which significantly
influences their bioactivity. As nanosized obligate intracellular parasites, viruses share …
influences their bioactivity. As nanosized obligate intracellular parasites, viruses share …
Cadmium in tobacco smokers: a neglected link to lung disease?
K Ganguly, B Levänen, L Palmberg… - European …, 2018 - Eur Respiratory Soc
Cadmium in tobacco smoke may contribute to the development of pulmonary emphysema.
However, there is poor understanding of the mechanisms behind the pathogenic role of …
However, there is poor understanding of the mechanisms behind the pathogenic role of …
Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin–lysoPA axis in COPD
…, S Snowden, T Heyder, B Levänen… - European …, 2017 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and a leading
cause of mortality and morbidity worldwide. The aim of this study was to investigate the sex …
cause of mortality and morbidity worldwide. The aim of this study was to investigate the sex …
Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD
…, S Snowden, R Karimi, B Levänen… - European …, 2016 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality; however,
the role of inflammatory mediators in its pathobiology remains unclear. The aim of this study …
the role of inflammatory mediators in its pathobiology remains unclear. The aim of this study …
[HTML][HTML] Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure
SL Lundström, B Levänen, M Nording… - PloS one, 2011 - journals.plos.org
Background Asthma is a chronic inflammatory lung disease that causes significant morbidity
and mortality worldwide. Air pollutants such as particulate matter (PM) and oxidants are …
and mortality worldwide. Air pollutants such as particulate matter (PM) and oxidants are …
Interleukin-26 in antibacterial host defense of human lungs. Effects on neutrophil mobilization
KF Che, S Tengvall, B Levänen, E Silverpil… - American journal of …, 2014 - atsjournals.org
Rationale: The role of the presumed Th17 cytokine IL-26 in antibacterial host defense of the
lungs is not known. Objectives: To characterize the role of IL-26 in antibacterial host defense …
lungs is not known. Objectives: To characterize the role of IL-26 in antibacterial host defense …
[HTML][HTML] The cytokine interleukin-26 as a biomarker in pediatric asthma
In this pilot study, we examined associations between local interleukin (IL)-26, disease
severity and biomarkers of Th2-mediated inflammation in a well-defined cohort of pediatric …
severity and biomarkers of Th2-mediated inflammation in a well-defined cohort of pediatric …
Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
BM Sundblad, J Ji, B Levänen, K Midander… - … journal of chronic …, 2016 - Taylor & Francis
Tobacco contains cadmium, and this metal has been attributed a causative role in pulmonary
emphysema among smokers, although extracellular cadmium has not to date been …
emphysema among smokers, although extracellular cadmium has not to date been …
[HTML][HTML] Interleukin-26 production in human primary bronchial epithelial cells in response to viral stimulation: modulation by Th17 cytokines
KF Che, R Kaarteenaho, E Lappi-Blanco, B Levänen… - Molecular …, 2017 - Springer
Interleukin (IL)-26 is abundant in human airways and this cytokine is involved in the local
immune response to a bacterial stimulus in vivo. Specifically, local exposure to the toll-like …
immune response to a bacterial stimulus in vivo. Specifically, local exposure to the toll-like …