Studies of the phenotype and population distribution of rare genetic forms of parkinsonism
are required, now that gene‐targeting approaches for Parkinson disease have reached the …

A (GGGGCC) n repeat expansion in C9orf72 gene is the major cause of frontotemporal
dementia (FTD) and amyotrophic lateral sclerosis (ALS). The relations between the repeats size …

C9orf72 repeat expansions are rarely associated with primary progressive aphasias (PPA).
In-depth characterization of the linguistic deficits, and the underlying patterns of grey-matter …

Objective To investigate cognitive inhibition in presymptomatic C9orf72 mutation carriers (C9+)
and its associated neuroanatomical correlates. Methods Thirty-eight presymptomatic …

Objective To examine the relationship between a Parkinson's disease (PD) polygenic risk
score (PRS) and impulse control disorders (ICDs) in PD. Background Genome wide …

Background Based on the hypothesis of a brain energy deficit, we investigated the safety and
efficacy of triheptanoin on paroxysmal episodes in patients with alternating hemiplegia of …

Background Progressive supranuclear palsy (PSP) is a rare parkinsonian syndrome with a
wide spectrum of clinical presentations. Recently, the MDS published revised diagnosis …

Muscle weakness is a major issue. An increased intracortical inhibition and a lack in central
motor drive have been recently reported in COPD (Alexandre et al., PLoS ONE 9:e100961, …

A high level of diversity has already been observed among the planets of our own Solar
System. As such, one expects extrasolar planets to present a wide range of distinctive features, …

Background: Genetic mutations causing autosomal recessive Parkinson's disease account
for a significant proportion of patients with early-onset disease. However, no large multicentre …