The impact of smoking cessation on respiratory symptoms, lung function, airway hyperresponsiveness and inflammation

BWM Willemse, DS Postma, W Timens… - European …, 2004 - Eur Respiratory Soc
Smoking is the main risk factor in the development of chronic obstructive pulmonary disease
(COPD), and smoking cessation is the only effective treatment for avoiding or reducing the …

[HTML][HTML] Development, validity and responsiveness of the Clinical COPD Questionnaire

T Van der Molen, BWM Willemse, S Schokker… - Health and quality of life …, 2003 - Springer
Background The new Global Obstructive Lung Disease (GOLD) guidelines advice to focus
treatment in Chronic Obstructive Pulmonary Disease (COPD) on improvement of functional …

[HTML][HTML] Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation

…, D Weill, MS Wijsenbeek, BWM Willemse… - The Journal of Heart and …, 2021 - Elsevier
Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral…

Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers

BWM Willemse, NHT ten Hacken… - European …, 2005 - Eur Respiratory Soc
Smoking cessation is the only treatment in patients with chronic obstructive pulmonary disease
(COPD) effective in slowing down disease progression. Its effect on airway inflammation …

[HTML][HTML] Acute effects of cigarette smoking on inflammation in healthy intermittent smokers

…, W Timens, MN Hylkema, BWM Willemse… - Respiratory …, 2005 - Springer
Background Chronic smoking is the main risk factor for chronic obstructive pulmonary
disease. Knowledge on the response to the initial smoke exposures might enhance the …

Increased number of B-cells in bronchial biopsies in COPD

MME Gosman, BWM Willemse… - European …, 2006 - Eur Respiratory Soc
Recently, it has been shown that the accumulated volume of B-cells in small airways is
increased in chronic obstructive pulmonary disease (COPD) Global Initiative for Chronic …

Untargeted lipidomic analysis in chronic obstructive pulmonary disease. Uncovering sphingolipids

…, R t'Kindt, SJM Hoonhorst, BWM Willemse… - American journal of …, 2014 - atsjournals.org
Rationale: Cigarette smoke is the major risk factor in the development of chronic obstructive
pulmonary disease (COPD). Lipidomics is a novel and emerging research field that may …

Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients

M van der Deen, H Marks, BWM Willemse, DS Postma… - Virchows Archiv, 2006 - Springer
Cigarette smoke is the principal risk factor for chronic obstructive pulmonary disease (COPD).
Multidrug resistance proteins, such as multidrug resistance-associated protein-1 (MRP1), P…

[HTML][HTML] Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers

BWM Willemse, NHT Ten Hacken, B Rutgers… - Respiratory …, 2005 - Springer
Background Inflammation in the airways and lung parenchyma underlies fixed airway
obstruction in chronic obstructive pulmonary disease. The exact role of smoking as promoting …

Smoking cessation improves both direct and indirect airway hyperresponsiveness in COPD

BWM Willemse, NHT ten Hacken… - European respiratory …, 2004 - Eur Respiratory Soc
Smoking induces chronic obstructive pulmonary disease (COPD) and is associated with
airway inflammation and airway hyperresponsiveness (AHR). It has not been studied in COPD …