Interstitial pulmonary fibrosis caused by the inhalation of asbestos fibers or silica particles
continues to be an important cause of interstitial lung disease. Although more stringent control …

Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …

A broad array of oxidative stresses modulates gene expression in a variety of mammalian
cells. One goal of this review was to characterize cellular responses to oxidative injury, how …

The inhalation of airborne pollutants, such as asbestos or silica, is linked to inflammation of
the lung, fibrosis, and lung cancer. How the presence of pathogenic dust is recognized and …

Asbestos is a commercial term for a group of fibrous minerals often associated with the
development of pulmonary interstitial fibrosis (asbestosis), lung cancer, and malignant …

We have demonstrated the selective induction of manganese superoxide dismutase (MnSOD)
or catalase mRNA after exposure of tracheobronchial epithelial cells in vitro to different …

ASBESTOS is a mineral causing much controversy in today's society. Before the passage
and enactment of the Occupational Safety and Health Act of 1970, millions of Americans were …

Asbestos is the main cause of human malignant mesothelioma (MM). In vivo, macrophages
phagocytize asbestos and, in response, release TNF-α and other cytokines that contribute to …

High levels of ambient air pollution are associated with exacerbation of asthma and respiratory
morbidity, yet little is known concerning the mechanisms of inflammation and toxicity by …

Exposure to asbestos causes cellular damage, leading to asbestosis, bronchogenic
carcinoma, and mesothelioma in humans. The pathogenesis of asbestos-related diseases is …