Regulators of A20 (TNFAIP3): new drug-able targets in inflammation
…, JR Naranjo, BC Schock - American Journal of …, 2019 - journals.physiology.org
Persistent activation of the transcription factor Nuclear factor-κB (NF-κB) is central to the
pathogenesis of many inflammatory disorders, including those of the lung such as cystic fibrosis (…
pathogenesis of many inflammatory disorders, including those of the lung such as cystic fibrosis (…
Bronchoalveolar lavage findings suggest two different forms of childhood asthma
…, G Turner, LG Heaney, BC Schock… - Clinical & …, 1997 - Wiley Online Library
Background It seems plausible that children with atopy and persistent asthma symptoms will,
like their adult counterparts, have chronic airways inflammation. However, many young …
like their adult counterparts, have chronic airways inflammation. However, many young …
Post-traumatic stress disorder: focus on neuroinflammation
J Li, L Tong, BC Schock, LL Ji - Molecular Neurobiology, 2023 - Springer
Post-traumatic stress disorder (PTSD), gaining increasing attention, is a multifaceted psychiatric
disorder that occurs following a stressful or traumatic event or series of events. Recently, …
disorder that occurs following a stressful or traumatic event or series of events. Recently, …
Ozone exposure activates oxidative stress responses in murine skin
G Valacchi, A Van der Vliet, BC Schock, T Okamoto… - Toxicology, 2002 - Elsevier
Ozone (O 3 ) is among the most reactive environmental oxidant to which skin is exposed. O
3 exposure has previously been shown to induce antioxidant depletion as well as lipid and …
3 exposure has previously been shown to induce antioxidant depletion as well as lipid and …
Gene expression profile of oxidant stress and neurodegeneration in transgenic mice deficient in α-tocopherol transfer protein
K Gohil, BC Schock, AA Chakraborty… - Free radical biology and …, 2003 - Elsevier
Alpha-tocopherol transfer protein (TTP) regulates the retention and secretion of α-tocopherol
(α-T) by the liver. Deletion of the TTP gene (Ttpa) in mice results in systemic deficiency of α-…
(α-T) by the liver. Deletion of the TTP gene (Ttpa) in mice results in systemic deficiency of α-…
Neutrophils and eosinophils: clinical implications of their appearance, presence and disappearance in asthma and COPD.
AP Watt, BC Schock, M Ennis - Current drug targets. Inflammation …, 2005 - europepmc.org
Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders.
Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with …
Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with …
Increased concentrations of the oxidative DNA adduct 7, 8-dihydro-8-oxo-2-deoxyguanosine in the germ-line of men with type 1 diabetes
IM Agbaje, CM McVicar, BC Schock, N McClure… - Reproductive …, 2008 - Elsevier
The effects of diabetes mellitus on male reproductive health have not been clearly defined.
A previous publication from this group reported significantly higher levels of nuclear DNA …
A previous publication from this group reported significantly higher levels of nuclear DNA …
Effect of fruit and vegetable intake on oxidative stress and inflammation in COPD: a randomised controlled trial
…, JM Bradley, CC Patterson, BC Schock… - European respiratory …, 2012 - Eur Respiratory Soc
Epidemiological evidence supports a positive relationship between fruit and vegetable (FV)
intake, lung function and chronic obstructive pulmonary disease (COPD). Increasing FV …
intake, lung function and chronic obstructive pulmonary disease (COPD). Increasing FV …
Chronic cough in children: bronchoalveolar lavage findings
PS Fitch, V Brown, BC Schock, R Taylor… - European …, 2000 - Eur Respiratory Soc
Isolated chronic cough in childhood is a common complaint. Although the symptom cough is
included in the definition of clildhood asthma, there is debate as to whether the majoritv of …
included in the definition of clildhood asthma, there is debate as to whether the majoritv of …
Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis
…, C Kelly, SD Zhang, BC Schock - Proceedings of the …, 2016 - National Acad Sciences
Cystic fibrosis (CF) lung disease is characterized by chronic and exaggerated inflammation
in the airways. Despite recent developments to therapeutically overcome the underlying …
in the airways. Despite recent developments to therapeutically overcome the underlying …