Early detection and treatment are critical for improving the outcome of patients with cancer 1
. Understanding the largely uncharted biology of carcinogenesis requires deciphering …

Induced pluripotent stem cells (iPSCs) hold great promise for modeling human hematopoietic
diseases. However, intrinsic variability in the capacities of different iPSC lines for …

Background Chronic mucus hypersecretion (CMH) is associated with an increased frequency
of respiratory infections, excess lung function decline, and increased hospitalisation and …

PURPOSE: Accurate assessment of the risk of malignancy (ROM) is critical in the management
of a screen-detected or incidental pulmonary nodule (PN) to minimize procedures for …

1581 Background: Multiple lines of evidence support the use of PPARγ ligands in the treatment
and prevention of lung cancer. Pioglitazone is a PPARγ ligand that is FDA-approved for …

Background CT screening for lung cancer results in a significant mortality reduction but is
complicated by invasive procedures performed for evaluation of the many detected benign …

102 Background: The immune response to frank malignancy has been the focus of published
work, but little is known about the adaptive immune response to bronchial premalignant …

COPD is characterized by emphysema with loss of extracellular matrix (ECM), and (small)
airways disease with increased ECM deposition and airway wall thickening. How both …

… DAUGS SAMUAL GARNER THEANNE LIU PAISLEY PARK TATIANA RICE DANIEL
SALMON AVI SPIRA JOSHUA WASBIN …

Introduction Interstitial lung abnormalities (ILA) often represent early fibrotic changes that
can portend a progressive fibrotic phenotype. In particular, the fibrotic subtype of ILA is …