User profiles for Audrey Tierney

Audrey C Tierney

University of Limerick
Verified email at ul.ie
Cited by 3674

Monounsaturated fatty acid–enriched high-fat diets impede adipose NLRP3 inflammasome–mediated IL-1β secretion and insulin resistance despite obesity

…, L McAllan, KN Nilaweera, ME O'Reilly, AC Tierney… - Diabetes, 2015 - Am Diabetes Assoc
Saturated fatty acid (SFA) high-fat diets (HFDs) enhance interleukin (IL)-1β–mediated adipose
inflammation and insulin resistance. However, the mechanisms by which different fatty …

Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome—LIPGENE: a European randomized dietary intervention …

AC Tierney, J McMonagle, DI Shaw… - International journal of …, 2011 - nature.com
Background: Excessive energy intake and obesity lead to the metabolic syndrome (MetS).
Dietary saturated fatty acids (SFAs) may be particularly detrimental on insulin sensitivity (SI) …

Obesity and body fat classification in the metabolic syndrome: impact on cardiometabolic risk metabotype

CM Phillips, AC Tierney, P Perez‐Martinez, C Defoort… - …, 2013 - Wiley Online Library
Objective: Obesity is a key factor in the development of the metabolic syndrome (MetS),
which is associated with increased cardiometabolic risk. We investigated whether obesity …

The effect of high-polyphenol extra virgin olive oil on cardiovascular risk factors: A systematic review and meta-analysis

…, AJ Reddy, A Forsyth, AC Tierney… - Critical reviews in …, 2019 - Taylor & Francis
The polyphenol fraction of extra-virgin olive oil may be partly responsible for its cardioprotective
effects. The aim of this systematic review and meta-analysis was to evaluate the effect of …

Prevalence of underprescription or overprescription of energy needs in critically ill mechanically ventilated adults as determined by indirect calorimetry: a systematic …

…, EJ Ridley, AC Tierney - Journal of Parenteral …, 2016 - Wiley Online Library
Background: Underfeeding and overfeeding has been associated with adverse patient
outcomes. Resting energy expenditure can be measured using indirect calorimetry. In its absence…

Targeted full energy and protein delivery in critically ill patients: a pilot randomized controlled trial (FEED trial)

K Fetterplace, AM Deane, A Tierney… - Journal of Parenteral …, 2018 - Wiley Online Library
Background International guidelines recommend greater protein delivery to critically ill
patients than they currently receive. This pilot randomized clinical trial aimed to determine …

[HTML][HTML] Practical dietary recommendations for the prevention and management of nonalcoholic fatty liver disease in adults

…, AJ Nicoll, M Ryan, S Sood, SK Roberts, AC Tierney - Advances in …, 2018 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. In the
absence of effective pharmacotherapies, clinical guidelines focus primarily on weight loss …

Serum vitamin D concentration does not predict insulin action or secretion in European subjects with the metabolic syndrome

HL Gulseth, IMF Gjelstad, AC Tierney… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE To investigate the relation between serum concentration of 25-hydroxyvitamin
D [25(OH)D] and insulin action and secretion. RESEARCH DESIGN AND METHODS In a …

[HTML][HTML] Gene-nutrient interactions in the metabolic syndrome: Single nucleotide polymorphisms in ADIPOQ and ADIPOR1interact with plasma saturated fatty acids to …

JF Ferguson, CM Phillips, AC Tierney… - The American journal of …, 2010 - Elsevier
Background: Progression of the metabolic syndrome (MetS) is determined by genetic and
environmental factors. Gene-environment interactions may be important in modulating the …

[HTML][HTML] A randomised controlled trial of a Mediterranean Dietary Intervention for Adults with Non Alcoholic Fatty Liver Disease (MEDINA): study protocol

…, MC Ryan, C Itsiopoulos, A Salim, AC Tierney - BMC …, 2016 - Springer
Background Non-alcoholic fatty liver disease, the most prevalent liver disease in developed
countries, remains difficult to manage with no proven safe and effective pharmacotherapy …