We elucidate grapevine evolution and domestication histories with 3525 cultivated and wild
accessions worldwide. In the Pleistocene, harsh climate drove the separation of wild grape …

Telomeres are the ends of eukaryotic chromosomes, consisting of consecutive short repeats
that protect chromosome ends from degradation. Telomeres shorten with each cell division, …

Introduction Autoinflammatory and autoimmune disorders are characterized by aberrant
changes in innate and adaptive immunity that may lead from an initial inflammatory state to an …

Colorectal cancer (CRC) arising in Lynch syndrome (LS) comprises tumours with constitutional
mutations in DNA mismatch repair genes. There is still a lack of whole‐genome and …

Investigating the role of host genetic factors in COVID-19 severity and susceptibility can
inform our understanding of the underlying biological mechanisms that influence adverse …

Gut microbiota-produced short chain fatty acids (SCFAs) play an important role in the
normal human metabolism and physiology. Although the gradients of SCFAs from the large …

Background Germinal center-derived B cell lymphomas are tumors of the lymphoid tissues
representing one of the most heterogeneous malignancies. Here we characterize the variety …

Background: The blood transcriptome is expected to provide a detailed picture of an organism's
physiological state with potential outcomes for applications in medical diagnostics and …

Background Space travel–associated stressors such as microgravity or radiation exposure
have been reported in astronauts after short‐ and long‐duration missions aboard the …

Surveillance of the evolving SARS-CoV-2 genome combined with epidemiological monitoring
and emerging vaccination became paramount tasks to control the pandemic which is …