Recently the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product has been
identified as a negative regulator of protein synthesis upstream of the mTOR and ribosomal …

GTPases of the Ras subfamily regulate a diverse array of cellular-signaling pathways,
coupling extracellular signals to the intracellular response machinery. Guanine nucleotide …

Physical inactivity is a cardinal feature of chronic obstructive pulmonary disease (COPD), and
is associated with increased morbidity and mortality. Pedometers, which have been used …

It has been claimed that the flavonoid genistein could be used to distinguish multidrug-resistant
tumors expressing the multidrug resistance-associated protein (MRP) from those …

Although the Ras subfamily of GTPases consists of ∼20 members, only a limited number of
guanine nucleotide exchange factors (GEFs) that couple extracellular stimuli to Ras protein …

Agronomic and quality traits were undoubtedly key issues for the domesticators of barley.
According to the archeological record, these early farmers used both wild and cultivated (non-…

The identification and location of sources of genetic resistance to plant diseases are
important contributions to the development of resistant varieties. The combination of different …

Epac-1 and -2 (exchange proteins directly activated by cyclic AMP) are guanine-nucleotide
exchange factors for the GTPases Rap1 and -2. Epac2 but not Epac1 was found to possess a …

Plant breeders regularly evaluate multiple traits across multiple environments, which opens
an avenue for using multiple traits in genomic prediction models. We assessed the potential …

Introduction and hypothesis The aim of this study was to evaluate the effectiveness of
transcutaneous posterior tibial nerve stimulation (TC PTNS) versus extended release oxybutynin (…