[HTML][HTML] The role of TAPSE/sPAP ratio in predicting pulmonary hypertension and mortality in the systemic sclerosis EUSTAR cohort

…, AM Hoffmann-Vold, C Pellicano, A Romaniello… - Autoimmunity …, 2023 - Elsevier
Objectives The study aim was to evaluate the predictive role of the echocardiography-derived
tricuspid annular plane systolic excursion/systolic pulmonary artery pressure (TAPSE/sPAP…

The paradox of pulmonary arterial hypertension in Italy in the COVID-19 era: is risk of disease progression around the corner?

…, M Mulè, G Paciocco, A Romaniello… - European …, 2022 - Eur Respiratory Soc
Objective The coronavirus disease 2019 (COVID-19) outbreak has led to significant restrictions
on routine medical care. We conducted a multicentre nationwide survey of patients with …

Pulmonary hypertension and clinical correlates in hypertrophic cardiomyopathy

…, G Tini, P Francia, A Maruotti, A Romaniello… - International Journal of …, 2017 - Elsevier
Background Pulmonary hypertension (PH) in patients with hypertrophic cardiomyopathy (HCM)
has been investigated in a small number of studies. Purpose of this study was to assess …

In systemic sclerosis, the TAPSE/sPAP ratio can be used in addition to the DETECT algorithm for pulmonary arterial hypertension diagnosis

…, G Leodori, A Gigante, A Romaniello… - …, 2022 - academic.oup.com
Objective Early detection of pulmonary arterial hypertension (PAH) is crucial for improving
patient outcomes. The aim of this study was to compare the positive predictive value (PPV) of …

Serum uric acid as a marker of microvascular damage in systemic sclerosis patients

…, S Quarta, ML Gasperini, F Di Mario, A Romaniello… - Microvascular …, 2016 - Elsevier
Background Microvascular damage of skin and internal organs is a hallmark of systemic
sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial …

[HTML][HTML] Interleukin-33 and soluble suppression of tumorigenicity 2 in scleroderma cardiac involvement

…, A Colalillo, C Ramaccini, A Romaniello… - Clinical and …, 2023 - Springer
Interleukin (IL)-33 is part of the IL-1 family of cytokines and soluble suppression of tumorigenicity
2 (sST2) is part of the family of IL-1 receptors. In systemic sclerosis (SSc), IL-33 and …

Circulating NT-proANP level is a predictor of mortality for systemic sclerosis: a retrospective study of an Italian cohort

A Romaniello, S Rubattu, V Vaiarello… - Expert Review of …, 2021 - Taylor & Francis
Objectives: The authors aimed to evaluate the role of N-terminal proANP (NT-proANP) and
of NT-proBNP circulating levels as predictive markers of death due to systemic sclerosis (SSc)…

Prepulse inhibition of the blink reflex by laser stimuli in normal humans

…, M Veciana, J Serra, G Cruccu, A Romaniello - Neuroscience …, 2000 - Elsevier
The subcortical integrative effects of laser-induced activation of pain ascending tracts were
examined in 11 healthy volunteers, aged 22–52 years. Subjects underwent either CO 2 laser …

The cardiac magnetic resonance in the diagnosis of cardiac Raynaud phenomenon in a patient with systemic sclerosis: case report and review of literature

…, N Galea, A Gigante, A Romaniello… - Expert Review of …, 2016 - Taylor & Francis
Raynaud phenomenon (RP) is the hallmark of Systemic Sclerosis (SSc). Visceral RP has
also been proposed in SSc patients. Cardiac Raynaud’s phenomenon (C-RP) was evaluated …

In systemic sclerosis patients, bosentan is safe and effective for digital ulcer prevention and it seems to attenuate the development of pulmonary arterial hypertension

A Romaniello, G Viola, F Salsano, E Rosato - Rheumatology, 2014 - academic.oup.com
SIR, SSc is a chronic connective tissue disease characterized by endothelial dysfunction and
fibrosis of the skin and internal organs. Vascular dysfunction is one of the hallmarks of SSc …