User profiles for Andreas Domen

Andreas Domen

MD, PhD
Verified email at uantwerpen.be
Cited by 232

[HTML][HTML] Cellular senescence in cancer: clinical detection and prognostic implications

A Domen, C Deben, J Verswyvel, T Flieswasser… - Journal of Experimental …, 2022 - Springer
Cellular senescence is a state of stable cell-cycle arrest with secretory features in response
to cellular stress. Historically, it has been considered as an endogenous evolutionary …

[HTML][HTML] Cancer-associated fibroblasts as a common orchestrator of therapy resistance in lung and pancreatic cancer

A Domen, D Quatannens, S Zanivan, C Deben… - Cancers, 2021 - mdpi.com
Simple Summary The tumor microenvironment (TME) is increasingly believed to be
involved in therapy resistance and disease progression of different cancer types. Cancer-associated …

[HTML][HTML] Prognostic implications of cellular senescence in resected non-small cell lung cancer

A Domen, C Deben, I De Pauw… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Background Cure and long-term survival for non-small cell lung cancer (NSCLC) remains
hard to achieve. Cellular senescence, an emerging hallmark of cancer, is considered as an …

[HTML][HTML] Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer

…, S Peeters, FR Fortes, C Hermans, A Domen… - NPJ Precision …, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases, characterized
by a treatment-resistant and invasive nature. In line with these inherent aggressive …

Multimodal management of malignant pleural mesothelioma: where are we today?

PE Van Schil, I Opitz, W Weder, C De Laet, A Domen… - 2014 - Eur Respiratory Soc
The prognosis of patients with malignant pleural mesothelioma remains poor and although it
is clear that multimodal therapy is necessary to improve long-term results, precise treatment …

[HTML][HTML] Immune checkpoint inhibitory therapy in sarcomas: is there light at the end of the tunnel?

V Siozopoulou, A Domen, K Zwaenepoel, A Van Beeck… - Cancers, 2021 - mdpi.com
Simple Summary Soft tissue and bone sarcomas is a very heterogeneous group of tumors
that has an aggressive course, especially in the metastatic setting. In this group the …

The role of Immunotherapy in esophageal and gastric cancer

H Dedecker, LA Teuwen, T Vandamme, A Domen… - Clinical colorectal …, 2023 - Elsevier
Upper gastrointestinal tract tumors historically have a poor prognosis. The decision to treat
esophageal or gastric cancers by surgery, radiotherapy, systemic therapy or a combination of …

[HTML][HTML] Characterization of acquired nutlin-3 resistant non-small cell lung cancer cells

C Deben, LF Boullosa, A Domen, A Wouters… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Aim: The purpose of this manuscript is to study the potential characteristics of acquired nutlin-3
resistant non-small cell lung cancer cells (NSCLC). Nutlin-3 is an inhibitor of the murine-…

Postoperative ileus after laparoscopic primary and incisional abdominal hernia repair with intraperitoneal mesh (DynaMesh®-IPOM versus Parietex™ Composite): a …

A Domen, C Stabel, R Jawad, N Duchateau… - … Archives of Surgery, 2021 - Springer
… data collection were performed by Andreas Domen, Cedric Stabel, … by Andreas Domen,
Cedric Stabel, and Erik Fransen. The first draft of the manuscript was written by Andreas Domen

[HTML][HTML] Extrapleural pneumonectomy: still indicated?

A Domen, L Berzenji, JMH Hendriks… - Translational Lung …, 2018 - ncbi.nlm.nih.gov
The optimal treatment of malignant pleural mesothelioma (MPM) has not yet been established
and is still under investigation. Surgery is one of the pillars in the multimodality approach …