A CMOS chip for individual cell manipulation and detection

…, G Medoro, L Altomare, A Leonardi… - IEEE Journal of Solid …, 2003 - ieeexplore.ieee.org
Manipulation of populations of living cells on an individual basis is essential for the investigation
of complex interactions among cells. We present a new approach to the integration on …

Ocular allergy: recognizing and diagnosing hypersensitivity disorders of the ocular surface

A Leonardi, E Bogacka, JL Fauquert, ML Kowalski… - Allergy, 2012 - Wiley Online Library
Ocular allergy includes several clinically different conditions that can be considered as
hypersensitivity disorders of the ocular surface. The classification of these conditions is complex, …

Vernal keratoconjunctivitis: pathogenesis and treatment

A Leonardi - Progress in retinal and eye research, 2002 - Elsevier
Vernal keratoconjunctivitis (VKC) is a recurrent or chronic ocular allergic disease that affects
mostly children and young adults living in warm climates worldwide. Understanding and …

Topical use of cyclosporine in the treatment of vernal keratoconjunctivitis

AG Secchi, MS Tognon, A Leonardi - American journal of ophthalmology, 1990 - Elsevier
We treated 11 patients with vernal keratoconjunctivitis for four to nine months with topical
cyclosporine as a 2% dilution in castor oil. No significant side effects occurred, except for mild …

Allergy and the eye

A Leonardi, L Motterle… - Clinical & Experimental …, 2008 - Wiley Online Library
The eye represents an ideal and frequent site for the allergic reactions. The term ‘allergic
conjunctivitis’ refers to a collection of disorders that affect the lid, conjunctiva and/or cornea. …

A lab-on-a-chip for cell detection and manipulation

G Medoro, N Manaresi, A Leonardi… - IEEE Sensors …, 2003 - ieeexplore.ieee.org
Presents a lab-on-a-chip for electronic manipulation and detection of microorganisms based
on the use of closed dielectrophoretic (DEP) cages combined with impedance sensing. A …

[HTML][HTML] Phase II randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis

…, L Mastropasqua, R Mencucci, J Dart, A Leonardi… - Ophthalmology, 2018 - Elsevier
Purpose To evaluate the safety and efficacy of topical recombinant human nerve growth
factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare degenerative …

Multiple cytokines in human tear specimens in seasonal and chronic allergic eye disease and in conjunctival fibroblast cultures

A Leonardi, SJ Curnow, H Zhan… - Clinical & Experimental …, 2006 - Wiley Online Library
Background Several cytokines are involved in the recruitment and activation of inflammatory
cells in ocular allergic diseases. The purpose of the study was to assay multiple cytokines …

Efficacy and safety of 0.1% cyclosporine A cationic emulsion in the treatment of severe dry eye disease: a multicenter randomized trial

A Leonardi, G Van Setten, M Amrane… - European journal of …, 2016 - journals.sagepub.com
Purpose The SANSIKA study was conducted to assess the treatment effect of 0.1% cyclosporine
A cationic emulsion (CsA CE) eye drops on signs and symptoms of patients with severe …

Immunopathogenesis of ocular allergy: a schematic approach to different clinical entities

A Leonardi, C De Dominicis… - Current opinion in allergy …, 2007 - journals.lww.com
A review of the recent literature allows us to better understand the mechanisms involved in
the development of ocular allergy and to guide us toward a more schematic approach, which …