Whole metagenome analysis has the potential to reveal functional triggers of skin diseases,
but issues of cost, robustness and sampling efficacy have limited its application. Here, we …

Abstract Characterization of microbiomes has been enabled by high-throughput metagenomic
sequencing. However, existing methods are not designed to combine reads from short- …

Background Nanopore sequencing provides a rapid, cheap and portable real-time sequencing
platform with the potential to revolutionize genomics. However, several applications are …

Although disinfection is key to infection control, the colonization patterns and resistomes of
hospital-environment microbes remain underexplored. We report the first extensive genomic …

Loss of diversity in the gut microbiome can persist for extended periods after antibiotic
treatment, impacting microbiome function, antimicrobial resistance and probably host health. …

Cholangiocarcinoma (CCA) is the primary cancer of the bile duct system. The role of bile duct
tissue microbiomes in CCA tumorigenesis is unestablished. To address this, sixty primary …

Understanding the composition and clinical importance of the fungal mycobiome was recently
identified as a key topic in a “research priorities” consensus statement for bronchiectasis. …

The gut microbiota possesses diverse metabolic activities, but its contribution toward
heterogeneous toxicological responses is poorly understood. In this study, we investigated the role …

Despite extensive efforts to address it, the vastness of uncharacterized ‘dark matter’
microbial genetic diversity can impact short-read sequencing based metagenomic studies. …

Background Even though human sweat is odorless, bacterial growth and decomposition of
specific odor precursors in it is believed to give rise to body odor in humans. While …