The impact of blood eosinophilia in chronic obstructive pulmonary disease (COPD) remains
controversial. To evaluate the prevalence and stability of a high level of blood eosinophils (…

The Bayesian analysis was used in this study to investigate the diagnostic value of the
bronchial provocation test with methacholine in patients with asthma. The best cutoff value of …

OBJECTIVE: This analysis of the cost of asthma in Spain includes both direct health care
costs and indirect costs arising from illness. PATIENTS AND METHODS: Prospective, 12-month …

Background Pulmonary hypertension in idiopathic pulmonary fibrosis (IPF) is indicative of a
poor prognosis. Recent evidence suggests that tetrahydrobiopterin (BH4), the cofactor of …

Patients with chronic obstructive pulmonary disease (COPD) often suffer episodes of
exacerbation (ECOPD) that impact negatively the course of their disease. ECOPD are …

This study has a twofold objective: 1) to explore to what extent suffering from asthma affects
the HRQL of men and women differently at several stages of disease severity and 2) to …

Dyspnea is a main feature of symptomatology in asthma, and its perception does not
necessarily correlates well with airway obstruction. The aim of this study was twofold: to identify …

Purpose Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical
symptoms and psychosocial effects that significantly impair patients’ quality of life. Refractory …

Non-T2 severe asthma and chronic obstructive pulmonary disease (COPD) are airway chronic
inflammatory disorders with a poor response to corticosteroids. LAS194046, a novel pan-…

Background The loss of corticosteroid efficacy is an important issue in severe asthma
management and may lead to poor asthma control and deterioration of airflow. Recent data …