Background In early life, the innate immune system can recognize both viable and nonviable
parts of microorganisms. Immune activation may direct the immune response, thus …

Asthma is caused by a combination of poorly understood genetic and environmental factors
1 , 2 . We have systematically mapped the effects of single nucleotide polymorphisms (SNPs…

The present guideline (S2k) on allergen-specific immunotherapy (AIT) was established by
the German, Austrian and Swiss professional associations for allergy in consensus with the …

BACKGROUND: Immunotherapy with the standardized quality grass tablet Grazax is
efficacious and well-tolerated in adult patients with rhinoconjunctivitis. Allergic asthma and …

Children of farmers are at decreased risk of developing allergies. Results of epidemiological
studies suggest increased exposure to microbial compounds might be responsible for this …

BACKGROUND: Children who grow up in a farming environment show lower levels of atopic
sensitization, hay fever, and asthma than children of the same age not living in such an …

Background Allergy immunotherapy targets the immunological cause of allergic
rhinoconjunctivitis and allergic asthma and has the potential to alter the natural course of allergic …

The major birch (Betula alba L.) pollen allergen, Bet v 1, has been shown to be homologous
to pathogenesis-related proteins in a number of plants. Recently, it was demonstrated that a …

BACKGROUND: Endotoxin exposure has been shown to be associated with a decreased
prevalence of atopic sensitization and symptoms. Yet endotoxin represents only a part of the …

Allergy today is a public health concern of pandemic proportions, affecting more than 150
million people in Europe alone. In view of epidemiological trends, the European Academy of …