Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

…, A Baxter-Stoltzfus, AC Borczuk… - Blood, The Journal …, 2020 - ashpublications.org
COVID-19 affects millions of patients worldwide, with clinical presentation ranging from
isolated thrombosis to acute respiratory distress syndrome (ARDS) requiring ventilator support. …

[HTML][HTML] COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City

AC Borczuk, SP Salvatore, SV Seshan, SS Patel… - Modern …, 2020 - nature.com
SARS-CoV-2, the etiologic agent of COVID-19, is a global pandemic with substantial mortality
dominated by acute respiratory distress syndrome. We systematically evaluated lungs of …

[HTML][HTML] The spatial landscape of lung pathology during COVID-19 progression

…, S Salvatore, CE Mason, EC Swanson, AC Borczuk… - Nature, 2021 - nature.com
Recent studies have provided insights into the pathology of and immune response to COVID-19
1 , 2 , 3 , 4 , 5 , 6 , 7 – 8 . However, a thorough investigation of the interplay between …

[HTML][HTML] PD-L1 immunohistochemistry comparability study in real-life clinical samples: results of blueprint phase 2 project

…, KM Kerr, M Kockx, MB Beasley, AC Borczuk… - Journal of Thoracic …, 2018 - Elsevier
Objectives The Blueprint (BP) Programmed Death Ligand 1 (PD-L1) Immunohistochemistry
Comparability Project is a pivotal academic/professional society and industrial collaboration …

[HTML][HTML] The 2021 WHO classification of lung tumors: impact of advances since 2015

…, MS Tsao, MB Beasley, AC Borczuk… - Journal of Thoracic …, 2022 - Elsevier
The 2021 WHO Classification of Thoracic Tumours was published earlier this year, with
classification of lung tumors being one of the chapters. The principles remain those of using …

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

…, JB Overdevest, PD Canoll, AC Borczuk… - Science translational …, 2022 - science.org
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae of …

Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 …

NK Altorki, TE McGraw, AC Borczuk, A Saxena… - The Lancet …, 2021 - thelancet.com
Background Previous phase 2 trials of neoadjuvant anti-PD-1 or anti-PD-L1 monotherapy in
patients with early-stage non-small-cell lung cancer have reported major pathological …

Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group

…, MB Beasley, AC Borczuk… - … of Pathology and …, 2013 - meridian.allenpress.com
Context.—Malignant mesothelioma (MM) is an uncommon tumor that can be difficult to diagnose.
Objective.—To provide updated practical guidelines for the pathologic diagnosis of MM…

[PDF][PDF] SARS-CoV-2 infection induces beta cell transdifferentiation

…, ACN Chong, LA Lacko, Z Min, JK Lim, AC Borczuk… - Cell metabolism, 2021 - cell.com
Recent clinical data have suggested a correlation between coronavirus disease 2019 (COVID-19)
and diabetes. Here, we describe the detection of SARS-CoV-2 viral antigen in …

[PDF][PDF] Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations

…, M Mansukhani, S Koul, B Halmos, AC Borczuk - J Clin …, 2016 - researchgate.net
… Western blotting of paired tumor– normal protein extracts from PSC showed smaller MET
protein in tumors and cell lines with MET exon 14 splice-site mutations but not in tumors …