Background. Mycobacterium abscessus can produce a chronic pulmonary infection for
which little is known regarding optimal treatment and long-term outcomes. Methods. We …

Rationale: Among patients with nontuberculous mycobacterial lung disease is a subset of
previously healthy women with a slender body morphotype, often with scoliosis and/or pectus …

Rationale: Currently recommended multidrug treatment regimens for Mycobacterium avium
complex (MAC) lung disease yield limited cure rates. This results, in part, from incomplete …

Background Clofazimine is an antimicrobial agent that has activity in vitro against mycobacteria.
Increasingly, it has been used for the treatment of nontuberculous mycobacteria (NTM), …

Purpose: Codon 12 mutations of K-ras are frequent in pancreatic adenocarcinoma, and
represent potential tumor-specific neoantigens. The objective of this study was to assess the …

Rationale: Mycobacterium abscessus is a significant threat to individuals with cystic fibrosis (CF)
because of innate drug resistance and potential transmission between patients. Recent …

Nontuberculous mycobacterial infections caused by Mycobacterium abscessus are
responsible for a range of disease manifestations from pulmonary to skin infections and are …

Purpose: PI-88 is a mixture of highly sulfated oligosaccharides that inhibits heparanase, an
extracellular matrix endoglycosidase, and the binding of angiogenic growth factors to …

Purpose: To describe patient/family and logistical barriers to participation in university-based,
early-phase cancer clinical trials for adults age ≥ 65 years, and to identify influences on …

Diagnosis of Mycobacterium avium complex pulmonary disease (MAC-PD) can be difficult.
A previous study from Japan reported the usefulness of a serodiagnostic test for MAC-PD. …