[HTML][HTML] Kinetics of neutrophil subsets in acute, subacute, and chronic inflammation

…, R Spijkerman, L Hesselink, AT Lo Tam Loi… - Frontiers in …, 2021 - frontiersin.org
At homeostasis the vast majority of neutrophils in the circulation expresses CD16 and
CD62L within a narrow expression range, but this quickly changes in disease. Little is known …

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia

…, BP Ramakers, VM Kamp, ALT Loi… - Journal of leukocyte …, 2010 - academic.oup.com
Adele Lo Tam Loi , Adele Lo Tam Loi … Janesh Pillay, Bart P Ramakers, Vera M Kamp, Adele
Lo Tam Loi, Siu W Lam, Falco Hietbrink, Luke P Leenen, Anton T Tool, Peter Pickkers, Leo …

[HTML][HTML] Advanced glycation endproducts and their receptor in different body compartments in COPD

SJM Hoonhorst, AT Lo Tam Loi, SD Pouwels, A Faiz… - Respiratory …, 2016 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a chronic lung disease
characterized by chronic airway inflammation and emphysema, and is caused by exposure to …

[HTML][HTML] Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD

…, W Timens, L Koenderman, AT Lo Tam Loi… - Respiratory …, 2014 - Springer
Background Cigarette smoking is the most important risk factor for Chronic Obstructive
Pulmonary Disease (COPD). Only a subgroup of smokers develops COPD and it is unclear why …

[HTML][HTML] Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients

ALT Loi, S Hoonhorst, C van Aalst, J Langereis… - Respiratory …, 2017 - Springer
Background COPD is a heterogeneous chronic inflammatory disease of the airways and it is
well accepted that the GOLD classification does not fully represent the complex clinical …

[HTML][HTML] Lower corticosteroid skin blanching response is associated with severe COPD

SJM Hoonhorst, NHT ten Hacken, AT Lo Tam Loi… - PloS one, 2014 - journals.plos.org
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow
limitation caused by ongoing inflammatory and remodeling processes of the airways and …

Advanced glycation end products in the skin are enhanced in COPD

SJM Hoonhorst, ATLT Loi, JE Hartman, ED Telenga… - Metabolism, 2014 - Elsevier
… Author links open overlay panel Susan JM Hoonhorst a b , Adèle T. Lo Tam Loi c , Jorine
E. Hartman a b , Eef D. Telenga a b , Maarten van den Berge a b , Leo Koenderman c , Jan …

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease …

ATLT Loi, SJM Hoonhorst, L Franciosi, R Bischoff… - Bmj Open, 2013 - bmjopen.bmj.com
Introduction Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease
with pulmonary and extra-pulmonary manifestations. Although COPD is a complex disease, …

Systemic inflammation in COPD: Is there a link with body composition?

ALT Loi, S Hoonhorst, N ten Hacken, JW Lammers… - 2011 - Eur Respiratory Soc
Introduction: COPD is characterized by a low grade systemic inflammation which has an effect
on body composition. We examined the relationship between systemic inflammation and …

Differences in responsiveness of blood neutrophils for fMLF indentify two distinct groups of COPD patients

V Kamp, ALT Loi, N ten Hacken, S Hoornhorst… - 2011 - Eur Respiratory Soc
In COPD severity of disease is generally diagnosed by the GOLD guidelines. The GOLD
stages, however, poorly correlate with disease progression. The extend of systemic …